摘要
目的:探讨骨皮质开窗病灶清除联合抗生素硫酸钙植入治疗儿童急性血源性骨髓炎的临床疗效。方法:回顾性分析本科2016年1月至2020年6月间收治的29例急性血源性骨髓炎患儿的临床资料,其中男17例,女12例;年龄2~16岁,平均10.3岁。所有患儿均接受了骨皮质开窗病灶清除联合抗生素硫酸钙植入术,对患儿的体温恢复时间、治疗效果、手术前后VAS评分及相关实验室检查进行记录比较。结果:29例患儿均顺利完成手术,随访时间8~55个月,平均24.8个月,所有患儿未出现病理性骨折等并发症,体温在1~7 d内恢复正常,平均2 d,2例患儿术后感染复发,经再次病灶清除抗生素硫酸钙植入后感染控制;患儿手术前后VAS评分、C-反应蛋白、血沉、白细胞相比,差异有统计学意义(P<0.05)。结论:骨皮质开窗病灶清除联合抗生素硫酸钙植入治疗儿童急性血源性骨髓炎,可以控制感染、缓解疼痛、降低患儿体温,值得临床推广应用。
Objective:To explore the clinical efficacy of debridement of bone cortical fenestration combined with antibiotics calcium sulfate on the treatment of children with acute hematogenous osteomyelitis.Methods:The clinical data of 29 children with acute osteomyelitis blood-borne from January 2016 to June 2020 were retrospectively analyzed including 17 males and 12 females,aged from 2 to 16 years old,with 10.3 years old on average.All of them accepted the bone cortex lesion clearance joint antibiotics calcium sulphate implantation,and the recovery days of body temperature,therapeutic efficacy,VAS scores before and after operation and related laboratory tests were recorded and compared.Results:All the 29 children completed the operation successfully,and the follow-up time was 8 to 55 months,with 24.8 months on average.There were no pathological fracture and other complications occurred in all the children.The body temperature returned to normal within 1 to 7 d with 2 d on average.The infection recurred in 2 children after surgery,and the infection was controlled after re-lesion clearance by antibiotics calcium sulfate implantation.The VAS scores,C-reactive protein,erythrocyte sedimentation rate and white blood cells were statistically significant before and after surgery.Conclusion:The combination of lesion clearance and antibiotics calcium sulfate implantation on the treatment of children with acute haematogenic osteomyelitis can effectively control infection,relieve pain and reduce the body temperature of children,which is worthy of clinical promotion.
作者
化昊天
王新卫
张磊
郭再冉
钟文龙
陈江非
王石林
HUA Haotian;WANG Xinwei;ZHANG Lei;GUO Zairan;ZHONG Wenlong;CHEN Jiangfei;WANG Shilin(Luoyang Orthopedic-Traumatological Hospital of Henan Province,Luoyang 471002,Henan China)
出处
《中国中医骨伤科杂志》
CAS
2022年第4期38-42,共5页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金
河南省科技攻关项目(182102310487)。
关键词
骨皮质开窗
病灶清除
抗生素硫酸钙
儿童
急性血源性骨髓炎
bone cortical fenestration
lesion removal
antibiotics calcium sulfate
children
acute blood-borne osteomyelitis
作者简介
通信作者:王新卫,E-mail:lywxw188@163.com。
