摘要
Microbial co-infections are another primary concern in patients with coronavirus disease 2019(COVID-19),yet it is an untouched area among researchers.Preliminary data and systematic reviews only show the type of pathogens responsible for that,but its pathophysiology is still unknown.Studies show that these microbial co-infections are hospital-acquired/nosocomial infections,and patients admitted to intensive care units with invasive mechanical ventilation are highly susceptible to it.Patients with COVID-19 had elevated inflammatory cytokines and a weakened cell-mediated immune response,with lower CD4+T and CD8+T cell counts,indicating vulnerability to various co-infections.Despite this,there are only a few studies that recommend the management of coinfections.
作者简介
Corresponding author:Henu Kumar Verma,PhD,Research Scientist,Senior Researcher,Department of Immunopathology,Institute of Lung Health and Immunity,Comprehensive Pneumology Center,Helmholtz Zentrum,Neuherberg Inglostäder Landstrapβe 1,Munich 85764,Germany.henu.verma@yahoo.com,Tarun Sahu 0000-0002-2721-7432;Henu Kumar Verma,0000-0003-1130-8783;Lakkakula V K S Bhaskar,0000-0003-2977-6454.
