摘要
日常饮食与机体的健康密切相关。食品的功能性成分在调节机体活性等方面发挥着至关重要的作用,已成为关注的热点,然而其具体机制不明确。microRNA(miRNA)作为一类非编码的小RNA分子,可通过调控靶基因的表达参与机体生命活动的调节。本文从miRNA出发,介绍miRNA介导人参皂苷、白藜芦醇、儿茶素、多不饱和脂肪酸、维生素等食品功能性成分,调节脂肪形成、心血管疾病、神经保护以及抗炎、抗癌的机制,为相关疾病的预防提供研究思路。
Daily diet is closely related to human health.The functional ingredients of daily diet play a vital role in regulating the activity of the body,which have become a hot spot of concern,but the specific mechanism is still unclear.microRNA(miRNA),a non-coding small RNA,could participate in the regulation of the body's life activities by regulating the expression of target gene.This article mainly starts from miRNA and focuses on miRNA in ginsenosides,resveratrol,catechin,polyunsaturated fatty acids,vitamins and other food and functional ingredients in regulating fat formation,cardiovascular disease,neuroprotection and anti-inflammatory and anti-cancer mechanisms.The aim is to explain the underlying mechanism of food and functional components regulating body activity and improving diseases from the perspective of miRNA,and provide ideas for the prevention of related diseases.
作者
杨超越
闫海洋
袁媛
Yang Chaoyue;Yan Haiyang;Yuan Yuan(College of Food Science and Engineering,Jilin University,Changchun 130062)
出处
《中国食品学报》
EI
CAS
CSCD
北大核心
2022年第3期361-368,共8页
Journal of Chinese Institute Of Food Science and Technology
基金
国家自然科学基金项目(32172322
31972181)。
作者简介
杨超越(1996—),女,硕士生;通信作者:袁媛,E-mail:yuan_yuan@jlu.edu.cn。
