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钬激光前列腺剜除术治疗良性前列腺增生合并尿潴留的有效性和安全性临床研究 被引量:7

Clinical efficacy and safety of holmium laser enucleation of prostate in the treatment of BPH with urinary retention
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摘要 目的 探讨钬激光前列腺剜除术治疗良性前列腺增生(BPH)合并尿潴留(UR)的有效性和安全性。方法 BPH病人198例,根据是否合并UR分为两组,UR组69例,伴有UR;非UR组129例,不伴UR。均行钬激光前列腺剜除手术,记录标本质量、手术时间、剜除时间、剜除率,术后尿管留置时间、膀胱冲洗时间、住院时间、血红蛋白变化值;统计术后并发症;术后1、3、6个月随访,记录其残余尿量(PVR)、最大尿流率(Qmax)、国际前列腺症状评分(IPSS)及生活质量评分(QoL)。结果 术前UR组病人尿白细胞阳性率、尿培养阳性率、PVR高于非UR组(P<0.05);UR组病人手术时间、剜除时间长于非UR组(P<0.05);两组病人剜除标本质量、剜除率、尿管留置时间、膀胱冲洗时间、住院时间、血红蛋白变化值、并发症发生率、术后PVR、IPSS、QoL、Qmax比较,差异无统计学意义(P>0.05);术后两组病人PVR、IPSS及QoL较术前均有下降,Qmax较术前增加,差异有统计学意义(P<0.05)。结论 钬激光前列腺剜除术治疗BPH合并UR病人效果良好、安全可靠。 Objective To investigate efficacy and safety of holmium laser enucleation of the prostate in the treatment of BPH with urinary retention(UR).Methods 198 patients with BPH were selected and divided into UR group(Sixty nine cases with UR) and non-UR group(129 cases without UR).Holmium laser enucleation of prostate was operated.The specimen quality, operation time, enucleation time, enucleation rate, postoperative urinary catheter indwelling time, bladder irrigation time, hospitalization time and hemoglobin change value were recorded.Postoperative complications were statistically analyzed.Patients were followed up for 1,3 and 6 months after operation, and their post-voiding residual(PVR),maximum urinary flow rate(Qmax),international prostatic symptom score(IPSS) and quality of life score(QoL) were recorded.Results The positive rates of urine white blood cells, urine culture and PVR in the UR group were higher than those in the non-UR group(P<0.05).The PVR,IPSS and QoL of the two groups were decreased compared with those before operation, and the Qmax was increased compared with that before operation(P<0.05).There was no significant difference in enucleation specimen quality, enucleation rate, indwelling time of urinary catheter, bladder irrigation time, hospitalization time, hemoglobin change value, incidence of complications, PVR,IPSS,QoL and Qmax between the two groups(P>0.05).The PVR,IPSS and QoL of the two groups were decreased compared with those before operation, and the Qmax was increased compared with that before operation(P<0.05).Conclusion Holmium laser enucleation of prostate is effective, safe and reliable in the treatment of BPH complicated with UR.
作者 陈赓 佘丽 王健 CHEN Geng;SHE Li;WANG Jian(Department of Urology,Nantong Second People's Hospital,Jiangsu,Nantong 226002,China)
出处 《临床外科杂志》 2022年第2期126-129,共4页 Journal of Clinical Surgery
基金 江苏省南通市卫健委课题(QA2020024)。
关键词 良性前列腺增生 尿潴留 钬激光前列腺剜除术 并发症 benign prostate hyperplasia urinary retention holmium laser enucleation of prostate complications
作者简介 通信作者:王健,Email:1228893325@qq.com。
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