摘要
随着生活方式的改变,2型糖尿病在青少年人群中发病率不断增加。青少年2型糖尿病既不同于1型糖尿病,也不同于成人2型糖尿病,相比成人发病的糖尿病病程进展更为快速、也更难治疗,防控形势严峻。本文结合第81届美国糖尿病协会科学年会相关热点和最新临床试验,对青少年2型糖尿病的流行病学现状、病理生理机制、危险因素、合并症、并发症以及其管理的循证证据等进行多层面梳理,以期为青少年2型糖尿病临床策略的制定提供参考。
With the changes of lifestyle,type 2 diabetes mellitus(T2DM)is spreading among the adolescents.T2DM in adolescents is distinct from type 1 diabetes mellitus and T2DM in adults.T2DM in adolescent progresses more rapidly and is more difficult to treat than that in adults.The prevention and therapy of T2DM in youth is facing severe challenges.This article reviews the epidemiology,pathophysiology,risk factors,comorbidities and complications of T2DM in adolescents as well as evidence-based clinical trials for the management of this disease based on the related hot spots of the 81st annual meeting of the American Diabetes Association and the results from the latest clinical trials,so as to provide enough reference for the formulation of clinical strategies of T2DM in adolescents.
作者
刘泽灏
孙嘉
Liu Zehao;Sun Jia(Department of Endocrinology,Xiangya Hospital,Central South University,Changsha 410008,China;Department of Endocrinology,Zhujiang Hospital,Southern Medical University,Guangzhou 510000,China)
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2022年第1期57-62,共6页
Chinese Journal of Endocrinology and Metabolism
关键词
糖尿病
2型
青少年
管理
美国糖尿病协会年会
Diabetes mellitus,type 2
Adolescent
Management
American Diabetes Association annual meeting
作者简介
通信作者:孙嘉,Email:sunjia@smu.edu.cn。