摘要
目的研究分析手术治疗时机对成年急性肠梗阻的治疗效果。方法简单随机选取2016年1月—2021年4月该院收治的成年急性肠梗阻患者80例为研究对象,遵照抽样法随机分为两组,其中40例患者为对照组,40例患者为观察组。对照组发病24 h后行急诊手术治疗,观察组发病24 h内行急诊手术治疗,以两组患者临床疗效、炎症因子水平、术后恢复情况、并发症为观察指标,比较观察结果。结果观察组临床总有效率高于对照组,差异有统计学意义(P<0.05)。观察组治疗后C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)水平分别为(5.32±1.11)、(1.78±0.22)mg/L,均低于对照组,差异有统计学意义(P<0.05);白细胞介素-2(IL-2)水平为(2.92±0.46)μg/L,显著高于对照组,差异有统计学意义(P<0.05)。观察组术后肛门排气时间、卧床时间、住院时间分别为(2.47±0.35)、(3.09±0.56)、(10.28±2.31)d,均短于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率显著低于对照组,差异有统计学意义(P<0.05)。结论成年急性肠梗阻患者发病24 h内行急诊手术治疗的效果更加确切,有助于减轻患者炎症反应,加快患者术后恢复,减少术后并发症的发生,临床应用价值非常高。
Objective To study and analyze the effect of surgical treatment timing on adult acute intestinal obstruction.Methods 80 adult patients with acute intestinal obstruction admitted to the hospital from January 2016 to April 2021 were simply randomly selected as the research objects.They were randomly divided into two groups according to the sampling method,40 patients in the control group and 40 patients in the observation group.The control group was treated with emergency operation after 24 h of onset,and the observation group was treated with emergency operation within 24 h of onset.The clinical efficacy,inflammatory factor level,postoperative recovery and complications of the two groups were observed,and the observation results were compared.Results The total clinical effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).The levels of C-reactive protein(CRP)and tumor necrosis factor-α(TNF-α)in the observation group after treatment were(5.32±1.11)mg/L and(1.78±0.22)mg/L,respectively,which were lower than those of the control group,the difference was statistically significant(P<0.05);interleukin-2(IL-2)level was(2.92±0.46)μg/L,which was significantly higher than the control group,and the difference was statistically significant(P<0.05).The postoperative anal exhaust time,bed time,and hospitalization time in the observation group were(2.47±0.35)d,(3.09±0.56)d,and(10.28±2.31)d,respectively,which were shorter than those of the control group,and the difference was statistically significant(P<0.05).The incidence of complications in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Results The effect of emergency surgery within 24 hours of the onset of adult acute intestinal obstruction is more accurate,which helps to reduce the inflammatory response of the patient,speed up the postoperative recovery of the patient,and reduce the occurrence of postoperative complications.The clinical application value is very high.
作者
徐潇
XU Xiao(Department of Gastrointestinal Surgery,Yixing People's Hospital,Yixing,Jiangsu Province,214200 China)
出处
《中外医疗》
2021年第36期81-84,共4页
China & Foreign Medical Treatment
关键词
急性肠梗阻
手术治疗时机
临床疗效
炎症因子
并发症
Acute intestinal obstruction
Timing of surgical treatment
Clinical efficacy
Inflammatory factors
Complications
作者简介
徐潇(1989-),男,硕士,主治医师,研究方向为胃肠肛肠。
