摘要
目的分析新生儿先天性甲状腺功能减低症(简称先天性甲低)的影响因素。方法选择75例确诊为先天性甲低的新生儿为病例组,同时纳入健康新生儿125例作为对照组。对两组新生儿及产妇的临床资料进行问卷调查,采用单因素分析、多因素Logistic回归分析探究新生儿先天性甲低的影响因素。结果多因素Logistic回归分析结果显示,年龄、受教育程度、孕期不良心理、妊娠合并甲状腺疾病、孕期高碘饮食是新生儿先天性甲低的危险因素,遵医嘱使用黄体酮为其保护因素(P<0.05)。结论产妇年龄、受教育程度、孕期不良心理、妊娠合并甲状腺疾病、孕期高碘饮食可诱导新生儿先天性甲低的发生,完善产前筛查、合理饮食、遵医嘱使用黄体酮可降低新生儿先天性甲低的发生风险。
Objective To analyze the influencing factors of neonatal congenital hypothyroidism.Methods Seventy-five newborns diagnosed with cogenital hypothyroidism were selected as case group,and 125 healthy newborns were included as control group.The clinical data of newborns and parturients in the two groups were investigated by questionnaire.The influencing factors of neonatal congenital hypothyroidism were explored by univariate analysis and multivariate Logistic regression analysis.Results The multivariate Logistic regression analysis showed that age,education level,adverse psychology during pregnancy,pregnancy complicated with thyroid disease and high iodine diet during pregnancy were the risk factors of neonatal congenital hypothyroidism,while using progesterone according to doctors'advice was the protective factor(P<0.05).Conclusion Maternal age,education level,adverse psychology during pregnancy,pregnancy complicated with thyroid disease and high iodine diet during pregnancy can induce the occurrence of neonatal congenital hypothyroidism.Improving prenatal screening,reasonable diet and using progesterone according to doctors'advice can reduce the risk of neonatal congenital hypothyroidism.
作者
祝玉平
师雪艳
ZHU Yuping;SHI Xueyan(the People's Hospital of Yuyang District/Yulin Children's Hospital,Yulin 719000,China)
出处
《临床医学研究与实践》
2022年第5期1-3,共3页
Clinical Research and Practice
基金
2020年青年人才托举计划项目(No.20200230)。
作者简介
祝玉平(1986-),女,汉族,河南西华人,主治医师,学士。研究方向:新生儿甲状腺功能低下;通讯作者:师雪艳,E-mail:897551528@qq.com.
