摘要
为探讨不同添加量山楂提取物(CF)对断奶仔猪生长性能、免疫功能、抗氧化能力和肠道微生物的影响,试验选择体重为(8.85±0.73)kg左右、健康状况良好的28日龄“杜×长×大”断奶仔猪30头,按体重相近的原则随机分为5组,每组6个重复,每个重复1头仔猪。对照组(CON组)饲喂基础日粮,抗生素组(CTC组)是在基础日粮中添加75 mg/kg金霉素,3个试验组分别在基础日粮中添加300、600、1200 mg/kg山楂提取物(CF1组、CF2组、CF3组),试验期28 d。结果表明:(1)与CON组相比,CF2组和CF3组断奶仔猪的末重(FBW)极显著提高(P<0.01),平均日增重(ADG)和采食量(ADFI)显著提高(P<0.05),料重比(F/G)和腹泻率显著降低(P<0.05)。与CTC组相比,CF2组和CF3组断奶仔猪的FBW、ADG和ADFI显著提高(P<0.05)。(2)与CON组相比,CF2组和CF3组血清中IgA含量显著提高(P<0.05),CF2组和CF3组之间的血清IgA差异不显著(P>0.05)。CF2组的血清IgM含量显著高于其余四组(P<0.05)。(3)CF2组和CF3组血清总超氧化物歧化酶(T-SOD)含量均显著高于CON组、CTC组和CF1组(P<0.05),CF2组和CF3组之间血清T-SOD含量差异不显著(P>0.05)。CF2组血清谷胱甘肽过氧化物酶(GSH-Px)显著高于其余四组(P<0.05)。与CON组相比,CF2组血清丙二醛(MDA)含量显著降低(P<0.05),其余各组血清MDA含量差异不显著(P>0.05)。(4)CF2组和CF3组结肠乳酸杆菌数量均显著高于CON组、CTC组和CF1组(P<0.05),CTC组、CF2组和CF3组结肠大肠杆菌数量显著低于CON组和CF1组(P<0.05),但CTC组、CF2组和CF3组之间结肠大肠杆菌数量差异不显著(P>0.05)。综上所述,CF2组即日粮添加600 mg/kg山楂提取物可提升断奶仔猪生长性能,降低腹泻率,改善免疫功能,提高抗氧化能力,改善肠道微生物菌群。
The objective of this study was to investigate the effects of different levels of crataegi fructus extract(CF)on growth performance,immune function,antioxidant capacity and intestinal microflora in weaned piglets.Thirty healthy crossbred(Duroc×Landrace×Yorkshire)piglets[(8.85±0.73)kg]were assessed at weaning(28 days)for initial body weight(BW)and randomly allotted to 5 groups with 6 replicates per group and 1 piglet per replicate.The dietary treatments of these 5 groups were as follows:The control group(CON group)was fed a basic diet.The antibiotic group(CTC group)was fed a basic diet supplemented with 75 mg/kg chlortetracycline.The three test groups respectively supplemented with 300,600,1200 mg/kg of CF into the basic diet(CF1 group,CF2 group and CF3 group).The piglets were restrictively housed and fed individually.The experiment lasted for 28 days.The experimental results showed that:(1)Compared with the CON group,the final BW,average daily gain(ADG),average daily feed intake(ADFI)of weaned piglets in CF2 and CF3 groups were significantly improved(P<0.05),and the feed-to-grain ratio and diarrhea rate of CF2 and CF3 groups were significantly reduced(P<0.05).Compared with the CTC group,the final BW,ADG,ADFI of weaned piglets in CF2 and CF3 groups were significantly improved(P<0.05).(2)Compared with the CON group,the concentrations of serum IgA in CF2 and CF3 groups was significantly increased(P<0.05),there was no significant effect on the concentrations of serum IgA between the CF2 and the CF3 groups(P>0.05).The concentrations of serum IgM in CF2 group was significantly higher than that in the other four groups(P<0.05).(3)The concentrations of serum total superoxide dismutase(T-SOD)in the CF2 and CF3 groups was significantly higher than that in the CON,CTC and CF1 groups(P<0.05),there was no significant effect on the concentrations of serum T-SOD between the CF2 group and the CF3 group(P>0.05).The concentrations of serum glutathione peroxidase(GSH-Px)in the CF2 group was significantly higher than that in the other four groups(P<0.05).Compared with the CON group,the concentrations of serum malondialdehyde(MDA)in the CF2 group was significantly decreased(P<0.05),while the concentrations of serum MDA content in other groups had no significant difference(P>0.05).(4)The counts of colonic Lactobacillus in the CF2 and CF3 groups was significantly higher than that in the CON,CTC and CF1 groups(P<0.05).The counts of colonic Escherichia coli in the CTC,CF2 and CF3 groups was significantly lower than that in the CON and CF1 groups(P<0.05),but there was no significantly effect on the counts of colonic Escherichia coli between the CTC,CF2 and CF3 groups(P<0.05).In conclusion,the supplementation of 600 mg/kg CF in the diet could improve the growth performance,reduce the rate of diarrhea,promote immunity and antioxidant capacity,as well as improve the intestinal microflora of weaned piglets.
作者
汤文杰
何鹏
刁慧
晏家友
魏小兰
周梦佳
黄崇波
邝声耀
李书伟
TANG Wenjie;HE Peng;DIAO Hui;YAN Jiayou;WEI Xiaolan;ZHOU Mengjia;HUANG Chongbo;KUANG Shengyao;LI Shuwei(Sichuan Animal Science Academy,Animal Breeding and Genetics Key Laboratory of Sichuan Province,Chengdu,Sichuan Province 610066,China;Livestock and Poultry Biological Products Key Laboratory of Sichuan Province,Sichuan Feed Science and Technology R&D Center,Sichuan Animetche Feed Co.Ltd,Chengdu,Sichuan Province 610066,China;Sichuan Animetche Biological development Co.Ltd,Chengdu,Sichuan Province 611330,China)
出处
《中国饲料》
北大核心
2022年第3期47-52,共6页
China Feed
基金
四川省应用基础项目(2018JY0641)。
关键词
山楂提取物
断奶仔猪
生长性能
免疫功能
抗氧化能力
肠道微生物
crataegi fructus extract
weaned piglets
growth performance
immune performance
antioxidant capacity
intestinal microflora
作者简介
汤文杰(1984-),男,硕士,副研究员,主要从事动物健康营养研究与新饲料添加剂研发,E-mail:13908093601@qq.com;通讯作者:李书伟(1969-),男,硕士,研究员,主要从事新饲料添加剂研发与应用示范,E-mail:lishuwei84511614@126.com。
