摘要
目的:探究临床药师在血液透析并发血流细菌感染、尿路真菌感染和肺部非典型病原体感染患者治疗中发挥的作用。方法:通过1例血液透析并发血流细菌感染、尿路真菌感染和肺部非典型病原体感染的患者,临床药师根据血液透析和药物的特点参与临床优化抗菌药物治疗方案的制定,根据患者肌酐清除率调整用药剂量并实施药学监护和出院带药的用药教育。结果:临床医师采纳药师建议,替考拉宁血药(谷)浓度达标,血培养与尿培养转阴,肺炎支原体抗体滴度下降;患者临床症状体征改善、炎性指标下降且无药物不良反应的发生。结论:临床药师参与治疗药物选择、剂量调整、药学监护和用药教育等,提高了其治疗效果,避免了药品不良反应的发生。
Objective:To explore the role of clinical pharmacists in the treatment of hemodialysis patients complicated with bloodstream bacterial infection,urinary tract fungal infection and lung atypical pathogen infection.Methods:By 1 case of hemodialysis complicated by bacterial infection,urinary tract fungal infection and blood flow to the lungs infection in patients with atypical pathogens,clinical pharmacists based on the characteristics of the hemodialysis and drug in clinical treatment plan formulation optimization of antimicrobial agents,and adjust dosage based on patients’creatinine clearance and implementation of pharmaceutical care and medication education of discharge with medication.Results:The clinician adopted the pharmacist’s suggestion,the blood drug(valley)concentration of teicolanin reached the standard,the blood bacteria culture and urine culture turned negative,and the antibody titer of mycoplasma pneumoniae decreased.The clinical symptoms and signs of the patients were improved,inflammatory indicators were decreased,and no adverse drug reactions occurred.Conclusion:Clinical pharmacists participated in drug selection,dose adjustment,pharmaceutical care and medication education,the therapeutic effect was improved and the occurrence of adverse drug reactions were avoided.
作者
张乃菊
刘金春
夏娟
陈重
吴缝婧
ZHANG Nai-ju;LIU Jin-chun;XIA Juan;CHEN Zhong;WU Feng-jing(The First Affiliated Hospital ofBengbu Medical College,Bengbu Anhui 233004,China;Nanjing Drum Tower Hospital Affiliated to School of Medicine of Nanjing University,Nanjing 210008,China)
出处
《抗感染药学》
2021年第11期1685-1688,共4页
Anti-infection Pharmacy
关键词
临床药师
血液透析
细菌感染
治疗方案
剂量调整
clinical pharmacist
hemodialysis
bacterial infection
treatment regimen
dose adjustment
作者简介
张乃菊(1981-),女,主管药师;通信作者:刘金春(1987-),男,硕士,主管药师【电子邮箱】:ziyuanznj@163.com。
