摘要
目的:基于循证医学手段,研究右美托咪定在全身麻醉(以下简称全麻)剖宫产术中对新生儿的影响。方法:计算机检索PubMed,EMBASE,The Cochrane Library和中国知网,收集右美托咪定在全麻剖宫产术中对新生儿的影响的临床随机对照试验。从纳入的研究中提取资料,并对其进行质量评价,再用RevMan 5.3软件进行Meta分析。结果:最终纳入6项随机对照试验,共256例患者。Meta分析结果显示:右美托咪定对全麻剖宫产术分娩时新生儿脐带血血气分析值、新生儿出生后1 min阿普加(Apgar)评分和5 min Apgar评分均无影响,差异无统计学意义(P>0.05)。结论:静脉注射右美托咪定不影响新生儿脐带血血气分析值和Apgar评分。
Objective:To evaluate the effect of dexmedetomidine on neonates in cesarean section under general anesthesia based on evidence-based medicine.Methods:Randomized controlled trials regarding the effect of dexmedetomidine on neonates in cesarean section under general anesthesia were searched in the databases PubMed,EMBASE,The Cochrane Library and CNKI.We extracted data and assessed the quality of the literature and adopted RevMan 5.3 to conduct meta-analysis on each effective index.Results:A total of 256 patients from 6 RCT studies were finally included.The meta-analysis showed,no differences existed in umbilical blood gases at delivery and Apgar scores at 1 minute and 5 minutes among two groups.Conclusion:Intravenous administration of dexmedetomidine could not affect the umbilical blood gases and Apgar score of the neonates.
作者
陈丽丽
廖建成
王阳娥
CHEN Lili;LIAO Jiancheng;WANG Yang′e(The People′s Hospital of Changning,Changning 421500,China)
出处
《临床医药实践》
2021年第12期899-903,共5页
Proceeding of Clinical Medicine
关键词
右美托咪定
剖宫产术
新生儿
循证医学
dexmedetomidine
cesarean section
neonates
evidence-based medicine
作者简介
陈丽丽(1977—),女,湖南省常宁市人,副主任医师,主要从事妇产科临床工作;通信作者:王阳娥。
