摘要
目的对胺碘酮联合美托洛尔治疗冠心病心律不齐的治疗效进行分析研究。方法选取2019年1月—2020年7月在该院治疗的冠心病心律不齐患者102例,使用随机数字法分为研究组和对照组,每组51例,其中研究组患者进行胺碘酮联合美托洛尔治疗,对照组患者单采用胺碘酮治疗,比较两组患者的疗效、心绞痛发作频率、血压变化、心律失常发作次数、持续时间以及发生的不良反应。结果研究组患者和对照组患者的治疗效果分别为94.1%和78.4%,差异有统计学意义(χ^(2)=5.298,P<0.05);治疗后,研究组患者的心绞痛发生频率少于对照组,差异有统计学意义(P<0.05);治疗后,研究组患者的收缩压和舒张压的改善情况优于对照组,差异有统计学意义(P<0.05);治疗后,研究组的心律失常发作次数和持续时间少于对照组,差异有统计学意义(P<0.05);研究组产生的不良反应患者有2例,不良反应率为3.9%,而对照组产生7例,不良反应率达到13.7%,差异无统计学意义(χ^(2)=1.950,P>0.05)。结论在冠心病心律不齐患者中使用胺碘酮联合美托洛尔治疗,能够改善患者疾病,缓解心律失常,减少发作次数,治疗效果显著,且具有较高的安全性。
Objective To analyze and study the therapeutic effect of amiodarone combined with metoprolol in the treatment of coronary heart disease arrhythmia.Methods A total of 102 patients with coronary heart disease with arrhythmia treated in the hospital from January 2019 to July 2020 were selected and divided into study group and control group by random number method,with 51 cases in each group.Patients in the study group were treated with amiodarone combined with metoprolol,and patients in the control group were treated with amiodarone alone.Compared the efficacy,frequency of angina pectoris,blood pressure changes,number of arrhythmia attacks,duration,and adverse reactions between the two groups of patients.Results The therapeutic effect of study group and control group was 94.1% and 78.4%,the difference was statistically significant(χ^(2)=5.298,P<0.05).After treatment,the frequency of angina pectoris in the study group was less than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the improvement of systolic and diastolic blood pressure in study group was better than that in control group,and the difference was statistically significant(P<0.05).After treatment,the frequency and duration of arrhythmia in the study group were less than those in the control group,and the difference was statistically significant(P<0.05).There were 2 patients in the study group with an adverse reaction rate of 3.9%,while there were 7 patients in the control group with an adverse reaction rate of 13.7%,and the difference was not statistically significant(χ^(2)=1.950,P>0.05).Conclusion The use of amiodarone combined with metoprolol therapy in patients with coronary heart disease and arrhythmia can improve the patient's disease,relieve arrhythmia,reduce the number of attacks.The treatment effect is remarkable,and has high safety.
作者
谢蒙伟
XIE Mengwei(Department of Cardiology,Guiyang Hospital,Guihang,Guiyang,Guizhou Province,550009 China)
出处
《系统医学》
2021年第21期77-79,88,共4页
Systems Medicine
关键词
胺碘酮
美托洛尔
冠心病
心律不齐
治疗效果
Amiodarone
Metoprolol
Coronary heart disease
Arrhythmia
Therapeutic effect
作者简介
谢蒙伟(1979-),男,硕士,副主任医师,主要从事心血管疾病介入诊疗工作。
