摘要
目的讨论盆腔肿瘤不同体位放疗致放射性直肠炎的临床分析。方法2018年1月—2020年6月便利选取120例接受放射治疗的盆腔肿瘤患者作为该次研究对象,以回顾性分析法了解70例仰卧位放射治疗与50例俯卧位放射治疗对放射性直肠炎发生率的影响。结果70例接受仰卧位放射治疗的盆腔肿瘤患者中共有44例(62.9%)出现放射性直肠炎。50例接受俯卧位放射治疗的盆腔肿瘤患者中共有17例(34.0%)出现放射性直肠炎。盆腔肿瘤经放疗后放射性直肠炎的发生与照射体位的差异有统计学意义(χ^(2)=11.027,P=0.004),且不同照射体位放射治疗引起的放射性直肠炎分度差异有统计学意义(χ^(2)=38.610,P<0.001)。放射性直肠炎发生与不同原发肿瘤、肿瘤的N分期及M分期的差异有统计学意义(P<0.05),而与性别、年龄、BSA、照射剂量、肿瘤的分化程度及T分期差异无统计学意义(P>0.05)。以放射性直肠炎发生与否为因变量,将相关参数纳入二元Logistic回归模型后发现照射体位(P=0.008)、原发肿瘤类型(P<0.001)、N1相对于N0分期(P=0.037)是影响放射性直肠炎发生的因素。结论盆腔肿瘤患者接受放射治疗后易引起放射性直肠炎,俯卧位更有利于减少和减轻放射性直肠炎。
Objective To discuss the clinical analysis of radiation proctitis induced by different position radiotherapy for pelvic tumor.Methods From January 2018 to Juned 2020,120 patients with pelvic tumors who received radiotherapy were selected conveniently as the subjects of this study.Use retrospective analysis to understand the influence of incidence of radiation proctitis in 70 cases of supine radiotherapy and 50 cases of prone radiotherapy.Results Radiation proctitis occurred in 44(62.9%)of 70 patients with pelvic tumors who received radiation therapy in the supine position.Radiation proctitis occurred in 17(34.0%)of 50 patients with pelvic tumors who received radiotherapy in the prone position.The incidence of radiation proctitis after radiotherapy of pelvic tumors was statistically significantly different from the radiation position(χ^(2)=11.027,P=0.004).And there was a statistically significant difference in the grades of radiation proctitis caused by radiotherapy in different irradiation positions(χ^(2)=38.610,P<0.001).There was a statistically significant difference between the occurrence of radiation proctitis and different primary tumors,tumor N staging and M staging(P<0.05).There was no statistically significant difference with gender,age,BSA,radiation dose,tumor differentiation and T stage(P>0.05).Taking the occurrence of radiation proctitis as the dependent variable,and incorporating relevant parameters into the binary Logistic regression model,found that,irradiation position(P=0.008),primary tumor type(P<0.001),N1 relative to N0 stage(P=0.037)were factors that affected the occurrence of radiation proctrris.Conclusion Patients with pelvic tumors are likely to cause radiation proctitis after receiving radiotherapy,and the prone position is more conducive to reducing and alleviating radiation proctitis.
作者
阙开乾
汤琅琅
李群
童远和
QUE Kaiqian;TANG Langlang;LI Qun;TONG Yuanhe(Department of Radiotherapy and Chemotherapy,Longyan First Hospital Affiliated to Fujian Medical University,Longyan,Fujian Province,364000 China;Department of Radiology,Longyan First Hospital Affiliated to Fujian Medical University,Longyan,Fujian Province,364000 China;Department of Radiotherapy,Sun Yat-sen University Affiliated Tumor Hospital,Guangzhou,Guangdong Province,510062 China)
出处
《中外医疗》
2021年第31期72-76,共5页
China & Foreign Medical Treatment
关键词
盆腔肿瘤
放射治疗
放疗体位
放射性直肠炎
Pelvic tumors
Radiotherapy
Radiotherapy position
Radiation proctitis
作者简介
阙开乾(1984-),男,硕士,主治医师,研究方向为肿瘤放疗。
