摘要
目的研究讨论"筋伤散"治疗膝关节骨性关节炎的临床疗效及效果。方法应用计算机数字随机排序的方式将本院2020年1月至2021年12月收治的120例膝关节骨性关节炎患者均分为对照组(60例,口服塞来昔布胶囊治疗)和治疗组(60例,采用外敷"筋伤散"治疗),对比患者治疗前后麦吉尔疼痛问卷(SF-MPQ)、西大略湖和麦克马斯特大学骨性关节炎指数积分(WOMAC)、膝关节KSS评分、血清白细胞介素1β(IL-1β)治疗有效率、症状积分、体征积分、生活质量以及治疗满意度。结果两组患者治疗前SFMPQ、WOCAC、KSS和IL-1β核磁共振筛查情况均无明显差异,无统计学意义(P> 0.05);治疗后,研究组患者SF-MPQ、WOCAC、IL-1β水平低于对照组,KSS评分高于对照组(P <0.05)。研究组治疗有效率为96.67%(58/60),对照组治疗有效率为85.00%(51/60),研究组患者治疗有效率高于对照组,差异显著,有统计学意义(P <0.05)。由症状积分以及体征积分数据上可见,治疗前两组数据对比差异不满足统计学意义(P> 0.05);治疗后,研究组症状积分以及体征积分较对照组低(P <0.05)。在生活质量评分数据方面,治疗前研究组生活质量与对照组比较差异无意义(P> 0.05),经治疗后研究组生活质量比较对照组高(P <0.05)。研究组治疗满意度为96.67%(58/60),对照组治疗满意度为81.67%(49/60)。由治疗满意度数据方面上可见,研究组治疗满意度较对照组较(P <0.05)。结论将"筋伤散"应用于膝关节骨性关节炎治疗中,不仅能大幅消除病症带来的疼痛,还能显著改善其膝关节功能,具有较高的临床应用价值。
Objective To study and discuss the clinical efficacy and effect of "Jinshang San" in the treatment of knee osteoarthritis. Methods The 120 patients with knee osteoarthritis admitted to our hospital from January 2020 to December 2021 were equally divided into the control group(60 cases,treated with oral celecoxib capsules) by means of computer-digital random sorting. And the treatment group(60 cases, treated with external application of "Jinshangsan"), compare the McGill Pain Questionnaire(SF-MPQ), Western Dalle Lake and McMaster University Osteoarthritis Index Score(WOMAC),before and after treatment. KSS score of knee joint, serum interleukin 1β(IL-1β) treatment effective rate, symptom score, physical sign score, quality of life and treatment satisfaction. Results There was no significant difference in SF-MPQ, WOCAC, KSS and IL-1β MRI screening between the two groups of patients before treatment, and there was no statistical significance(P>0.05). After treatment, patients in the study group had SF-MPQ, WOCAC, the IL-1β level was lower than the control group, and the KSS score was higher than that of the control group. The effective rate of treatment in the study group is 96.67%(58/60);the effective rate in the control group is 85.00%(51/60). After treatment, it can be seen that the effective rate of treatment in the study group is higher than that in the control group. The difference is significant, and there are statistics. Academic significance(P<0.05). It can be seen from the data of symptom score and physical sign score that the difference in data comparison between the two groups before treatment did not meet the statistical significance(P>0.05). After treatment, the symptom score and physical sign score of the study group were lower than those of the control group(P<0.05).From the quality of life score data, it can be seen that the quality of life of the study group before treatment and the control group is not significant(P>0.05), and the quality of life of the study group after treatment is higher than that of the control group(P<0.05). The treatment satisfaction of the study group was 96.67%(58/60);the treatment satisfaction of the control group was 81.67%(49/60). It can be seen from the treatment satisfaction data that the treatment satisfaction of the study group is higher than that of the control group(P<0.05). Conclusion The application of "Jinshang San" in the treatment of knee osteoarthritis can not only greatly eliminate the pain caused by the disease, but also significantly improve the function of the knee joint, which has high clinical application value.
作者
张新娟
胡可
王芳
陆军伟
翟宇新
ZHANG Xinjuan;HU Ke;WANG Fang;LU Junwei;ZHAI Yuxin(Jiangyin City Hospital of Traditional Chinese Medicine,Jiangyin 214400,China)
出处
《中国医药指南》
2021年第35期4-6,共3页
Guide of China Medicine
基金
无锡市卫生健康委科研项目(MS201943)。
关键词
膝关节骨性关节炎
筋伤散
治疗有效率
症状积分
体征积分
生活质量
治疗满意度
Knee osteoarthritis
Jinshangsan
Effective rate of treatment
Symptom score
Physical sign score
Quality of life
Treatment satisfaction
