摘要
目的分析北京市城市地区结直肠癌高危人群内镜筛查依从性及相关影响因素,为优化城市结直肠癌筛查项目管理提供数据支持和对策建议。方法选取2016—2019年北京市城市癌症早诊早治结直肠癌项目参与人群,采用多因素logistic回归模型分析影响结直肠癌高危人群内镜筛查依从性的相关因素。结果73240名北京市40~69岁健康居民纳入风险评估,评估出结直肠癌高危人群12135人,问卷初筛高危率16.57%;完成内镜筛查3061例,参与率25.22%。内镜筛查依从性存在年份和城区差异。多因素logistic回归分析显示,年龄≥60岁(OR=0.84,95%CI:0.74~0.95)、受教育水平为高中/中专(OR=0.78,95%CI:0.71~0.86)、大学/大专及以上(OR=0.88,95%CI:0.79~0.97)、每周体育锻炼≥3次(OR=0.89,95%CI:0.82~0.97)的人群接受内镜筛查依从性较差;而家庭做饭油烟较多(OR=1.76,95%CI:1.46~2.13)、常饮酒(OR=1.22,95%CI:1.11~1.34)、有精神创伤或压抑史(OR=1.37,95%CI:1.25~1.50)、有结直肠疾病史(OR=16.65,95%CI:15.25~18.18)、有癌症家族史(OR=2.30,95%CI:2.10~2.52)的人群依从性相对较好(P<0.05)。结论北京市城市地区结直肠癌高危人群的内镜筛查依从性仍待提高,应针对不同特征人群进行精准健康管理,提升结直肠癌高危人群内镜检查的总体依从性,提高内镜检查人群覆盖率,实现结直肠癌早诊早治,最终服务健康中国建设。
Objective To analyze the compliance with endoscopic screening for colorectal cancer and related influencing factors among high-risk population in urban areas of Beijing from 2016 to 2019,and to provide data support and countermeasure suggestions for optimizing the management of urban colorectal cancer screening programs.Methods Participants who enrolled in the 2016-2019 Beijing Urban Cancer Early Detection and Treatment Colorectal Cancer Project were selected in the questionnaire survey.A multi-factor logistic regression model was used to analyze the factors associated with the compliance to endoscopic screening for colorectal cancer among high risk population.Results A total of 73240 healthy residents aged 40-69 years in Beijing were included in the risk assessment for colorectal cancer and 12135 individuals were assessed as being at high risk of colorectal cancer,with a high risk rate of 16.57%.3061(25.22%)participants received endoscopic screening.There were spatio-temporal differences in endoscopic screening compliance of participants.Multivariate logistic regression analysis showed that participants with older age(≥60)(OR=0.84,95%CI:0.74-0.95),with higher education level(high school/secondary specialized school:OR=0.78,95%CI:0.71-0.86;university/college and above:OR=0.88,95%CI:0.79-0.97)and with physical activity≥3 times per week(OR=0.89,95%CI:0.82-0.97)were less likely to comply with the screening,while those with a lot home cooking(OR=1.76,95%CI:1.46-2.13),drinking alcohol(OR=1.22,95%CI:1.11-1.34),trauma or depression(OR=1.37,95%CI:1.25-1.50),history of colorectal diseases(OR=16.65,95%CI:15.25-18.18)and a family history of cancer(OR=2.30,95%CI:2.10-2.52)were more likely to comply with endoscopic screening(P<0.05).Conclusions Endoscopic screening compliance of individuals with high-risk colorectal cancer in urban areas of Beijing still needs to be improved.All relevant factors should be considered and appropriate interventions should be actively taken to improve the overall compliance with endoscopy among individuals at high risk of colorectal cancer in order for the early diagnosis and treatment of cancer.
作者
顾芳慧
杨雷
张希
李晴雨
刘硕
李慧超
王宁
季加孚
GU Fang-hui;YANG Lei;ZHANG Xi;LI Qing-yu;LIU Shuo;LI Hui-chao;WANG Ning;JI Jia-fu(Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Peking University Cancer Hospital&Institute,Beijing 100142,China)
出处
《中国预防医学杂志》
CAS
CSCD
北大核心
2021年第6期428-433,共6页
Chinese Preventive Medicine
基金
北京学者计划(2017-030)
北京市医院管理中心2021年度“培育计划”管理项目(PG2021021)
北京肿瘤医院科学研究基金资助项目(2020自主-10)。
关键词
直肠癌
结肠镜
筛查
依从性
对策
Colorectal cancer
Colonoscopy
Screening
Compliance
Countermeasures
作者简介
顾芳慧,硕士研究生,助理研究员,主要从事公共卫生和医院管理研究;通信作者:王宁,E-mail:bjwangning@126.com。
