摘要
目的研究全身骨扫描(whole body scan,WBS)联合靶/非靶比值(target/non-target,T/NT)对骨转移瘤的诊断价值。方法选取2019年1月2日至2020年11月25日收治的157例疑似骨转移瘤患者纳入研究。对所有受试者均开展全身骨扫描,借助GE公司后处理软件系统测量并计算T/NT。以病理诊断结果为金标准,分析不同检查方式诊断骨转移瘤的效能。此外,对比不同骨转移瘤病灶T/NT的差异。结果经病理确诊157例疑似骨转移瘤患者中有骨转移瘤病灶75例,良性病变病灶82例。骨转移瘤病灶的T/NT为(12.40±3.15),明显高于良性病变病灶(6.69±2.01),差异有统计学意义(P <0.05)。以病理诊断结果为金标准,全身骨扫描联合T/NT诊断骨转移瘤的灵敏度、特异度及准确度分别为93.33%、95.12%、94.27%,均高于全身骨扫描的81.33%、85.37%、83.44%以及T/NT的68.00%、81.71%、75.16%,差异有统计学意义(均P <0.05)。肋骨骨转移瘤病灶T/NT低于盆骨、脊柱以及其他部位骨转移瘤病灶,且盆骨骨转移瘤病灶T/NT低于脊柱以及其他部位骨转移瘤病灶(均P <0.05)。结论全身骨扫描与T/NT联合诊断骨转移瘤具有较高的灵敏度以及特异度。
Objective To study and analyze the value of whole-body bone scanning(WBS)combined with target/non-target ratio(T/NT)in the diagnosis of bone metastases. Methods A total of 157 patients with suspected bone metastases admitted to our hospital from January 2,2019 to November 25,2020 were included in this study. WBS were performed on all subjects,and T/NT was measured and calculated using a GE post-processing software system. The results of pathological diagnosis were used as the gold standard to analyze the efficacy of different examination methods in the diagnosis of bone metastases. In addition,the differences of T/NT in different bone metastases were compared. Results The results of pathological diagnosis showed that there were 75 cases of bone metastases and 82 cases of benign lesions among 157 suspected patients with bone metastases. The T/NT of patients with bone metastases was(12.40 ± 3.15),which was significantly higher than that of patients with benign lesions(6.69 ± 2.01),and the difference was statistically significant(P < 0.05). The sensitivity,specificity and accuracy of WBS combined with T/NT in the diagnosis of bone metastases were 93.33%,95.12% and 94.27% respectively,according to the pathological diagnosis results as the gold standard. All of them were higher than those of WBS(81.33%,85.37%,83.44%)and T/NT(68.00%,81.71%,75.16%). The difference was statistically significant(all P < 0.05). T/NT of bone metastases from ribs was lower than that of bone metastases from pelvis,spine and other sites,and T/NT of bone metastases from pelvis was lower than that of bone metastases from spine and other sites(all P < 0.05). Conclusion WBS combined with T/NT has high sensitivity and specificity in the diagnosis of bone metastases.
作者
郑洪
温必辉
ZHENG Hong;WEN Bihui(Department of Nuclear Medicine,the Affiliated Yuebei People′s Hospital of Shantou University Medical College,Shaoguan 512026,China)
出处
《实用医学杂志》
CAS
北大核心
2021年第21期2795-2798,共4页
The Journal of Practical Medicine
基金
韶关市卫生健康科研项目(编号:Y21139)。
关键词
骨转移瘤
全身骨扫描
靶/非靶比值
诊断价值
bone metastases
full-body bone scan
target/non-target ratio
diagnostic value
