摘要
亚临床甲状腺功能减退症(SCH)是指在游离甲状腺激素浓度正常的情况下促甲状腺激素(TSH)水平升高,即使甲状腺激素水平的微小变化也会改变心血管功能。SCH与心律失常、致命和非致命冠状动脉疾病(CAD)事件及充血性心力衰竭的风险增加相关。文章主要综述了SCH引起心血管疾病(CVD)风险增加的可能机制,以及SCH与心律失常、CAD、心力衰竭的联系,并阐述了SCH的治疗对CVD的影响。
Subclinical hypothyroidism(SCH)refers to the increase of thyroid stimulating hormone(TSH)level when the concentration of free thyroid hormone is normal.Even small changes in thyroid hormone level will change cardiovascular function.Sch is associated with an increased risk of arrhythmias,fatal and nonfatal coronary artery disease(CAD)events,and congestive heart failure.This paper mainly reviews the possible mechanism of increased risk of cardiovascular disease(CVD)caused by Sch,the relationship between Sch and arrhythmia,CAD and heart failure,and expounds the effect of SCH treatment on CVD.
作者
刘云韦(综述)
时立新(审校)
Liu Yunwei;Shi Lixin(Graduate School of Guizhou Medical University,Guizhou Province,Guiyang 550004,China;不详)
出处
《疑难病杂志》
CAS
2021年第12期1268-1272,共5页
Chinese Journal of Difficult and Complicated Cases
基金
科技部国家重点研发计划精准医学专项(2016YFC0901203)。
作者简介
通信作者:时立新,E-mail:slx1962@medmail.com.cn。
