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原发性失眠患者睡眠脑电生理特征研究 被引量:1

Sleep electrophysiological characteristics in patients with primary insomnia
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摘要 目的:探讨原发性失眠患者睡眠脑电生理特征。方法:选择2019年6月至2021年6月九江市第一人民医院收治的30例原发性失眠患者作为研究组,另选取同期进行体检的30例健康志愿者作为对照组,性别不限,年龄21~59岁。对两组研究对象进行多导睡眠图监测,分析两组研究对象的睡眠总时间(TST)、睡眠潜伏期(SL)、睡后觉醒次数(AN)、觉醒总时间(AT)、睡眠效率(SE)、睡眠维持率(SM)、S1、S2阶段的睡眠时间、觉睡比(AT/TST)和快速眼动睡眠时间(RT)、快速眼动睡眠潜伏期(RL)、快速眼动活动度(RA)、快速眼动强度(RI)和快速眼动密度(RD)等睡眠脑电生理特征。结果:研究组TST、SE以及SM均小于对照组,SL、AN以及AT均大于对照组,差异均有统计学意义(P<0.05)。研究组S1、S2以及RT均短于对照组,AT/TST大于对照组,差异均有统计学意义(P<0.05)。研究组RL、RA、RI以及RD均大于对照组(P<0.05)。结论:原发性失眠患者的睡眠模式主要表现为睡眠潜伏期延长,睡后觉醒次数和觉醒总时间增多,快波睡眠活动幅度较大较强,睡眠效率降低。 Objective: To study the electrophysiological characteristics in patients with primary insomnia. Methods: Thirty patients with primary insomnia in Jiujiang No.1 People’s Hospital from June 2019 to June 2021 were selected as the study group, and 30 healthy volunteers who underwent physical examination in the same period were selected as the control group, both of sexes, aged 21-59 years. The polysomnography was used to monitor the total sleep time(TST), sleep latency(SL), awakening numbers(AN), awakening time(AT), sleep efficiency(SE), sleep maintenance rate(SM), sleep time in S1 and S2 stages, AT/TST and rapid eye movement sleep time(RT), REM sleep latency(RL), REM activity(RA), REM intensity(RI), and REM density(RD). Results: TST,SE and SM in the study group were lower than those in the control group, and SL, AN and AT were higher than those in the control group(P<0.05). S1, S2 and RT in the study group were shorter than those in the control group, and AT/TST was higher than that in the control group, with statistical significance(P<0.05). RL, RA, RI and RD in the study group were higher than those in the control group(P<0.05). Conclusion: The sleep patterns of patients with primary insomnia are mainly characterized by prolonged sleep latency, increased awakening numbers and total wake-up time after sleep, larger and stronger REM activity and lower sleep efficiency.
作者 李芳 Li Fang(Department of General Practice Medicine,Jiujiang No.1 People's Hospital,Jiujiang City,Jiangxi Province,332000,China)
出处 《现代电生理学杂志》 2021年第4期225-228,共4页 Journal of Modern Electrophysiology
关键词 失眠症 电生理学 多导睡眠监测 Insomnia Electrophysiology Polysomnography
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