摘要
目的分析肝动脉化疗栓塞联合射频消融术用于肝癌治疗的有效性与生存情况。方法选择该院2014年1月-2019年1月收治的肝癌患者共120例,数字表随机分两组,每组60例。对照组的患者给予单纯肝动脉化疗栓塞治疗,观察组采取肝动脉化疗栓塞联合射频消融术。比较两组1年生存率、治疗前后患者生存质量评分、甲胎蛋白含量水平、肿瘤最大直径水平、治疗6个月后总有效率。结果观察组1年生存率(83.33%)高于对照组(66.67%),差异有统计学意义(χ^(2)=4.444,P<0.05)。观察组生存质量评分显著高于对照组,甲胎蛋白含量水平、肿瘤最大直径水平显著低于对照组,差异有统计学意义(P<0.05)。观察组治疗6个月后总有效率(83.33%)高于对照组(66.67%),差异有统计学意义(χ^(2)=4.444,P<0.05)。结论肝动脉化疗栓塞联合射频消融术治疗肝癌效果确切,可有效降低甲胎蛋白和缩小肿瘤,提高治疗效果,增加生存率和改善生存质量。
Objective To analyze the effectiveness and survival of hepatic artery chemoembolization combined with radiofrequency ablation for the treatment of liver cancer.Methods A total of 120 patients with liver cancer in the hospital from January 2014 to January 2019 were selected.The digital table was randomly divided into two groups of 60 patients.Patients in the control group were treated with hepatic artery chemoembolization alone,and the observation group was treated with hepatic artery chemoembolization combined radiofrequency ablation.The 1-year survival rate,the quality of life scores before and after treatment,the level of alpha-fetoprotein,the maximum diameter of the tumor,and the total effective rate after 6 months of treatment were compared between the two groups.Results The 1-year survival rate of the observation group(83.33%)was higher than that of the control group(66.67%),and the difference was statistically significant(χ^(2)=4.444,P<0.05).The quality of life score of the observation group was significantly higher than that of the control group,and the levels of alpha-fetoprotein and the maximum tumor diameter were significantly lower than those of the control group,and the difference was statistically significant(P<0.05).The total effective rate of the observation group after 6 months of treatment(83.33%)was higher than that of the control group(66.67%),and the difference was statistically significant(χ^(2)=4.444,P<0.05).Conclusion Hepatic artery chemoembolization combined with radiofrequency ablation has a definite effect in the treatment of liver cancer.It can effectively reduce alpha-fetoprotein and shrink tumors,improve the therapeutic effect,increase survival rate and improve quality of life.
作者
丁文刚
DING Wengang(Department of General Surgery,Huimin County People's Hospital,Binzhou,Shandong Province,251700 China)
出处
《系统医学》
2021年第19期114-116,共3页
Systems Medicine
关键词
肝动脉化疗栓塞
射频消融术
单纯肝动脉化疗栓塞
肝癌
生存质量
生存率
Hepatic artery chemoembolization
Radiofrequency ablation
Simple hepatic artery chemoembolization
Liver cancer
Quality of life
Survival rate
作者简介
丁文刚(1979-),男,本科,主治医师,研究方向为胃肠、肝胆、两腺专业。
