摘要
目的探究气管支气管结核经全身抗结核治疗同时辅以经支气管镜注药的治疗效果。方法简单随机选取2018年7月-2020年7月该院收治的60例气管支气管结核患者作为研究对象,分为参照组与研究组,各30例。参照组实施全身抗结核治疗,研究组添加经支气管镜注药治疗,对比两组患者治疗效果、痰菌转阴率、并发症发生率。结果治疗3个月后,研究组患者有效率为93.33%、治疗12个月后,有效率为96.67%,均优于参照组,差异有统计学意义(χ^(2)=12.272、9.017,P<0.05)。研究组患者治疗3个月痰菌转阴率为90.00%、治疗12个月痰菌转阴率为93.33%,均优于参照组为50.00%、60.00%,差异有统计学意义(χ^(2)=11.428、9.317,P<0.05)。治疗后,研究组不良反应发生率为6.27%低于参照组的26.67%,差异有统计学意义(χ^(2)=4.320,P<0.05)。结论气管支气管结核患者采用经全身抗结核联合经支气管镜注药治疗,有效缓解临床症状,提高治疗有效率,治疗效果显著,可在临床推广及使用。
Objective To explore the therapeutic effect of systemic anti-tuberculosis treatment for tracheobronchial tuberculosis and bronchoscopy.Methods 60 patients with tracheobronchial tuberculosis treated in the hospital from July 2018 to July 2020 were selected simple randomly as the research object and divided into the reference group and the study group,with 30 cases in each group.The control group adopted bronchoscopy treatment,the treatment effect,sputum conversion rate and the conplication rate were compared.Results After 3 months of treatment,the effective rate of the study group was 93.33%,after 12 months of treatment,the effective rate was 96.67%,which was better than the reference group,and the difference was statistically significant(χ^(2)=12.272,9.017,P<0.05).The sputum bacteria negative conversion rate 90.00%in the study group after 3 months of treatment and 93.33%,after 12 months of treatment were better than those in the reference group 50.00%and 60.00%,the difference were statistically significant(χ^(2)=11.428,9.317,P<0.05).After treatment,the incidence of adverse reactions in the study group was 6.27%,which was lower than 26.67%in the reference group,and the difference was statistically significant(χ^(2)=4.320,P<0.05).Conclusion Patients with tracheobronchial tuberculosis are treated with systemic anti-tuberculosis combined with bronchoscope injection,which can effectively relieve the clinical symptoms,improve the treatment efficiency,and have a significant therapeutic effect.It can be promoted and used in clinical practice.
作者
王海荣
武晓
孙丽梅
李同霞
WANG Hairong;WU Xiao;SUN Limei;LI Tongxia(Department of Thoracic Medicine,Qingdao Chest Hospital,Qingdao,Shandong Province,266043 China;Department of Respiratory and Critical Care Medicine,Qingdao Central Hospital,Qingdao,Shandong Province,266043 China)
出处
《中外医疗》
2021年第28期53-55,151,共4页
China & Foreign Medical Treatment
关键词
气管支气管结核
全身抗结核治疗
经支气管镜注药
不同时期
Tracheobronchial tuberculosis
Systemic anti-tuberculosis treatment
Bronchoscope injection
Different periods
作者简介
王海荣(1979-),女,硕士,主治医师,研究方向为结核病及危重症学。
