摘要
目的探讨MRI在老年首发精神分裂症患者中的应用价值。方法选取我院2018年3月~2019年3月收治的45例老年首发精神分裂症患者作为观察组,同期选取45例健康体检者作为对照组。观察两组MRI检查结果及观察组在不同脑部结构异常治疗效果的差异。结果观察组的左、右侧侧脑室面积、距胼胝体的垂直长度、距胼胝体下缘水平线长度、距大脑中线长度、穹隆脚中段部位厚度及紧贴胼胝体处厚度的MRI检测水平均高于对照组,两组差异有统计学意义(P<0.05)。观察组中皮质萎缩患者在MRI诊断疗效上明显高于同侧脑室扩大伴皮质萎缩及脑室呈对称性扩大,差异有统计学意义(P<0.05)。与正常对照组相比,观察组的正常脑非对称性明显降低,颞上回右侧大于左侧的非对称性减低,丘脑左侧大于右侧的非对称性明显减低并消失。结论MRI在老年首发精神分裂症患者不同脑部扫描检测中效果显著,可证明患者脑部存在一定的结构异常,且不同结构异常与临床治疗效果存在相关性,对皮质萎缩的患者具有较好的疗效,安全可靠,在临床工作中值得推广应用。
Objective To analyze the application value of 1.5T MRI in different brain abnormal scanning and curative effect evaluation of the elderly patients with first-episode schizophrenia.Methods 45 patients were served as the observation group and 45 health examiners were acted as the control group from March 2018 to March 2019.MRI test results of two groups and different brain structure abnormalities of the observation group were compared.Results The area of left and right lateral ventricles,the vertical length from the corpus callosum,the horizontal length from the inferior margin of the corpus callosum,the length from the midline of the brain,the thickness of the middle part of the fornix foot and the thickness near the corpus callosum in the observation group were all higher than those in the control group(P<0.05).In the observation group,the curative effect of MRI in the patients with cortical atrophy was significantly higher than that in the patients with ipsilateral ventricular enlargement accompanied by cortical atrophy and symmetrical ventricular enlargement,the difference was statistically significant(P<0.05).Compared with the control group,the asymmetry of the normal brain in the observation group was significantly reduced,that of the right superior temporal gyrus was greater than that of the left,and that of the left thalamus was greater than that of the right.Conclusion1.5 T MRI was effective in different brain scans of patients with first-episode schizophrenia.It could prove that there were certain structural abnormalities in the brain of patients,and it had good curative effect on patients with cortical atrophy,which was safe,reliable,and worthy of popularization and application in clinical practice.
作者
潘安光
马邦程
陈旺强
PAN Anguang;MA Bangcheng;CHEN Wangqiang(Department of Radiology, Wenzhou Seventh People's Hospital, Wenzhou 325005, P.R.China)
出处
《医学影像学杂志》
2021年第11期1842-1845,共4页
Journal of Medical Imaging
基金
浙江省温州市科学技术局公益性科技计划项目(编号:Y20170839)。
关键词
精神分裂症
老年患者
脑部扫描
磁共振成像
疗效评估
Schizophrenia
Elderly patients
Brain scan
Magnetic resonance imaging
Efficacy evaluation
作者简介
潘安光(1981-),男,毕业于温州医学院,本科学历,主治医师,主要从事医学影像学诊断工作。
