摘要
火把花根片是以卫矛科雷公藤属植物昆明山海棠去皮的根芯制备而成的中成药,临床研究表明其是一种高效低毒的药物,具有抗炎、镇痛、免疫抑制等类似激素样作用,目前主要用于自身免疫相关疾病的治疗,如类风湿性关节炎、系统性红斑狼疮等,取得了较好的疗效。对近20年火把花根片的相关文献进行整理,分析和归纳火把花根片的药理学作用和临床应用,以期为其后续临床精准用药提供药理学和临床治疗学依据。
Huobahuagen Tablets is a Chinese patent medicine prepared from the peeled root of Tripterygium hypoglaucum(Lévl.)Hutch. Clinical studies have shown that the Huobahuagen piece is a kind of efficient and low toxicity drugs, have anti-inflammatory and analgesic, immunosuppression and similar hormone kind function. At present, huobahuagen piece has achieved a good therapeutic effect in the treatment of rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, etc and have achieved good efficacy. The related literature of Huobahuagen Tablets in the past 20 years are sorted and the pharmacological effects and clinical applications of Huobahuagen Tablets were analyzed and summarized to provide pharmacological and clinical therapeutic evidence for subsequent clinical precision treatment.
作者
钟颖
赵潇
赵建权
甘奇超
史景彦
黄娜娜
孙蓉
ZHONG Ying;ZHAO Xiao;ZHAO Jianquan;GAN Qichao;SHI Jingyan;HUANG Nana;SUN Rong(The Second Hospital,Cheeloo College of Medicine,Shandong University,Jinan 250033,China;Tianjin University of Traditional Chinese Medicine(TCM),Tianjin 301617,China;Pharmceutical Factory of the Chongqing Academy of Chinese Mataria Medica,Chongqing 400800,China;Advanced Medical Research Institute,Cheeloo College of Medicine,Shandong University,Jinan 250012,China)
出处
《药物评价研究》
CAS
2021年第9期2020-2027,共8页
Drug Evaluation Research
基金
国家自然基金面上项目(81773997)
国家重点基础研究发展计划(973)中医基础理论专项资助项目(2009CB522802)
泰山学者工程专项经费项目(Ns201511107)。
关键词
火把花根片
昆明山海棠
抗炎
镇痛
免疫抑制
类风湿关节炎
Huobahuagen Tablets
pharmacological effects
clinical application
Tripterygium hypoglaucum
作者简介
第一作者:钟颖,女,硕士研究生,主要从事内科学与中医药转化研究。E-mail:17865197806@163.com;通信作者:孙蓉,女,二级教授,博士生导师,主要从事中药药理与毒理研究。E-mail:sunrong107@163.com。
