摘要
目的:比较飞秒激光辅助的准分子激光原位角膜磨镶术(FS-LASIK)与FS-LASIK联合快速角膜胶原交联术(FS-LASIK Xtra)矫正高度近视术后早期屈光度及角膜高阶像差变化特点,评估两种术式矫正高度近视的早期效果。方法:回顾性病例对照研究。纳入2019-04/2020-04在我院进行FS-LASIK Xtra及FS-LASIK的高度近视患者42例84眼,每组各21例42眼,术后随访3mo,比较两组患者术后裸眼视力(UCVA)、等效球镜(SE)、散光度及角膜高阶像差。结果:FS-LASIK Xtra组患者术后1d UCVA(LogMAR)低于FS-LASIK组(P<0.01),其余时间点两组间比较均无差异(P>0.05)。两组患者术后SE均较术前明显降低,术后3mo,FS-LASIK Xtra组有38眼(90%)、FS-LASIK组有41眼(98%)术眼SE在±1.00D以内。两组患者术后均有35眼(83%)的术眼残余散光在0.50D以内。两组术后3mo角膜总高阶像差、球差、彗差及三叶草差均较术前增大,FS-LASIK Xtra组总高阶像差及三叶草差大于FS-LASIK组(均P<0.05)。结论:FS-LASIK与FS-LASIK Xtra矫正高度近视在术后早期均具有较好的有效性和可预测性,术后早期角膜总高阶像差均增加,且行FS-LASIK Xtra增加更显著。
AIM:To compare the change of refractive power and corneal high-order aberrations after femtosecond laser-assisted excimer laser in situ keratomileusis(FS-LASIK)and FS-LASIK combined with accelerated corneal cross-linking(FS-LASIK Xtra)for high myopia correction,and to evaluate the early effects of two surgical methods to correct high myopia.METHODS:Retrospective case-control study.Totally 42 patients(84 eyes)with high myopia underwent FS-LASIK Xtra and FS-LASIK in our hospital from April 2019 to April 2020 were followed up for 3mo,including 21 patients in each group(42 eyes).The uncorrected visual acuity(UCVA),spherical equivalent(SE),astigmatism and corneal high-order aberration of the two groups were analyzed and compared.RESULTS:The UCVA of the FS-LASIK Xtra group was significantly lower than that of the FS-LASIK group at 1d after surgery(P<0.01),there was no statistical difference in UCVA at the other time points after surgery between the two groups(P>0.05).The postoperative SE of the two groups was significantly lower than that before surgery,at 3mo after surgery,38 eyes(90%)in the FS-LASIK Xtra group and 41 eyes(98%)in the FS-LASIK group had SE within±1.00D.In both groups,35 eyes(83%)had residual astigmatism within 0.50D after surgery.The total corneal high-order aberrations,spherical aberrations,coma and clover aberrations in the two groups were increased at 3mo after surgery,the total high-order aberration and clover aberration in the FS-LASIK Xtra group were greater than those in the FS-LASIK group(all P<0.05).CONCLUSION:FS-LASIK and FS-LASIK Xtra have good effectiveness and predictability in correcting high myopia in the early postoperative period,the total high-order aberrations of the cornea both increased in the early postoperative period,and the patients who underwent FS-LASIK Xtra were increased significantly.
作者
曹文佳
申笛
王晓睿
王亚妮
孙西宇
韦伟
Wen-Jia Cao;Di Shen;Xiao-Rui Wang;Ya-Ni Wang;Xi-Yu Sun;Wei Wei(The First Affiliated Hospital of Northwestern University, Xi'an First Hospital, Shaanxi Institute of Ophthalmology, Xi'an 710001, Shaanxi Province, China)
出处
《国际眼科杂志》
CAS
北大核心
2021年第12期2161-2165,共5页
International Eye Science
基金
陕西省重点研发计划项目(No.2018SF-216)
陕西省自然科学基础研究计划——一般(面上)项目(No.2021JM-593)。
关键词
飞秒激光
高度近视
角膜胶原交联
屈光度
角膜高阶像差
femtosecond laser
high myopia
corneal collagen cross-linking
refractive power
corneal high-order aberration
作者简介
曹文佳,硕士,住院医师,研究方向:屈光手术;通讯作者:韦伟,硕士,副主任医师,研究方向:眼视光学、屈光手术,wills2015@foxmail.com。
