摘要
目的分析在儿童重症肌无力(MG)患者的随访过程中,采用服药依从性宣教方案降低疾病复发率的有效性。方法根据儿童MG护理随访经验,制作《重症肌无力患者服药依从性调查表》和宣教方案,采用克朗巴赫系数(Cronbach′s Alpha,CA)进行信度检测。选取2016年1月—2019年6月在重庆医科大学附属儿童医院诊断并住院治疗的儿童MG患者331例,根据患者入科时间先后顺序及医生查房组空床收治情况随机分为对照组100例和观察组231例。对照组常规宣教,观察组在常规宣教基础上,从住院后首次服药开始对患者监护人实施服药依从性宣教方案。患者出院前一天、患者出院后第7天、出院第37天均采用《重症肌无力患者服药依从性调查表》对照护人进行调查评分。结果《重症肌无力患者服药依从性调查表》的总表信度为0.922。观察组自行停药3例,对照组自行停药9例(P<0.001)。不规律服药的患者中,观察组出现复发者3例,对照组出现复发者9例(P<0.001);规律服药的患者中,观察组出现复发者1例,对照组出现复发者5例(P<0.05)。结论儿童MG患者服药过程中,对监护人施行服药依从性宣教方案可以有效降低患者不规律服药和自行停药的发生率,从而保证正规治疗方案及疗程的有效完成,提高疗效。
Objective To analyze the effectiveness of medication compliance health education program(MCHEP)in reducing the recurrence rate of children with myasthenia gravis(MG)in the follow-up process.Methods According to the follow-up experience of children's MG nursing,the compliance Questionnaire Scale(CQS)and the Health Education Program(HEP)were developed,and the Cronbach's Alpha(CA)was used to evaluated the reliability.A total of 331 MG patients diagnosed and hospitalized in Children's Hospital affiliated to Chongqing Medical University from January 2016 to June 2019 were randomly divided into control group(100 patients cation compliance education)and observation group(231 patients)according to the order of admission to the department.The control group adopted routine education,the observation group was based on the control group and children with the Guardians of the patients were given the CQS and HEP after HEP was given the guardians of the patients in the control group the day before discharge,the 7th of day and 37th day after discharge investigated and scored with CQS compared with nurse.Results The CA of the CQS showed that the reliability of the master table was 0.922.The drug withdrawal was noted in 3 and 9 patients in the observation group and control group respectively(P<0.001).In the patients had irregular medication,the recurrence was showed in 3 and 9 patients in the observation group and control group respectively(P<0.001).In the patients had regular medication,the recurrence was showed in 1 and 5 patients in the observation group and control group respectively(P<0.05).Conclusion The CQS for guardians of children diagnosed of MG after the first administration of medicine can effectively reduce the incidence of irregular medication and self-withdrawal,and to ensure a regular treatment program and the course of treatment,and ultimately improve the efficacy.
作者
李曦
吴晓英
陈文劲
谢玲玲
黄翠
李佳承
LI Xi;WU Xiaoying;CHEN Wenjin;XIE Lingling;HUANG Cui;LI Jiacheng(Children′s Hospital of Chongqing Medical University,Chongqing 400014,China)
关键词
重症肌无力
服药依从性
宣教方案
复发
Myasthenia gravis
Medication compliance
Compliance questionnaire scale
Recurrence
作者简介
李曦,女,本科,护师;通信作者:陈文劲。
