摘要
目的探讨妇炎康片联合阿奇霉素对慢性盆腔炎患者炎症介质及不良反应的影响。方法选取2018年6月至2019年6月于营口市老边区人民医院就诊的60例慢性盆腔炎患者作为研究对象,依据治疗方式不同分为对照组(采用阿奇霉素,30例)与试验组(采用妇炎康片+阿奇霉素,30例),比较两组临床疗效、炎症介质、症状评分及不良反应。结果试验组治疗有效率96.67%,高于对照组的73.33%(P<0.05);试验组治疗后C反应蛋白(CRP)水平低于对照组,白细胞介素-10(IL-10)水平高于对照组,差异有统计学意义(P<0.05);试验组治疗后下腹疼痛、腰骶胀痛、带下异常评分低于对照组(P<0.05);试验组不良反应发生率为16.67%,对照组不良反应发生率为6.67%,差异无统计学意义(P>0.05)。结论应用妇炎康片联合阿奇霉素治疗慢性盆腔炎,临床治疗效果显著,可有效调节CRP、IL-10水平,改善临床症状,具有一定用药安全性。
Objective To explore the clinical effect of Fuyankang Tablets combined with azithromycin on inflammatory mediators and adverse reactions of patients with chronic pelvic.Methods A total 60 patients with chronic pelvic inflammation treated admitted to People’s Hospital of Yingkou Old Border District from June 2018 to June 2019 were selected as the research objects.According to the different treatment methods,they were divided into a control group(30 patients with azithromycin)and a test group(30 patients with Fuyankang Tablets+azithromycin).The clinical efficacy,inflammatory mediators,symptom scores and adverse reactions of the 2 groups were compared.Results The effective rate of treatment in the test group was 96.67%,which was higher than 73.33%in the control group(P<0.05);the C-reactive protein(CRP)level after treatment in the test group was lower than that in the control group,and the level of interleukin-10(IL-10)was higher than that in the control group,the difference was statistically significant(P<0.05);the scores of lower abdominal pain,lumbosacral distension,and sub-band abnormalities after treatment in the test group were lower than those in the control group(P<0.05);the adverse reaction rate in the test group was 16.67%.The incidence of adverse reactions in the control group was 6.67%,and the difference was not statistically significant(P>0.05).Conclusion The application of Fuyankang Tablets combined with azithromycin in the treatment of chronic pelvic inflammatory disease has a significant clinical treatment effect,which can effectively regulate the levels of CRP and IL-10,improve clinical symptoms,and has certain medication safety.
作者
谭娜
TAN Na(Department of Obstetrics and Gynecology',People's Hospital ofYingkou Old Border District,Yingkou 115005,China)
出处
《中国药物经济学》
2021年第9期49-51,55,共4页
China Journal of Pharmaceutical Economics
关键词
慢性盆腔炎
妇炎康片
阿奇霉素
Chronic pelvic inflammatory disease
Fuyankang Tablet
Azithromycin
