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微生物制备高光学纯度L-乳酸的研究进展 被引量:10

Progress in Microbiological Preparation of L-lactic Acid Strain with High Optical Purity and Its Production
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摘要 L-乳酸(L(+)-Lactic acid),分子式为C3H6O3可以被人体所代谢,在食品、医药、日化和工业各个领域有广泛的应用。而生产L-乳酸的方法,化学合成法、酶法、微生物制备发酵法中,微生物制备发酵法具有成本低廉、产出量大、简单方便等优势。本文首先从菌株的不同种类分析了微生物发酵产L-乳酸的优势,随后介绍了已经开发出的L-乳酸的优化工艺,包括菌种发酵所使用的原料、所能适应的发酵条件、产酸所能达到的光学纯度及目前工业化生产的发酵水平,希望为工业化的大生产提供理论基础。 L-lactic acid,whose molecular formula is C3H6O3,can be metabolized by human body,which can be widely used in various fields such as food,medicine,daily chemical and industry.However,in the production of L-lactic acid,chemical synthesis,enzymatic method and microbial preparation and fermentation method,microbial preparation and fermentation method has the advantages of low cost,large yield,simplicity and convenience.First of all,this article from the strain of kinds of alternative analysis is made of the advantages of microbial fermentation to produce L-lactic acid,then introduced have developed the optimization technology of L-lactic acid,including strains used in fermentation raw materials,can adapt to the fermentation conditions and the fermentation level in the industrial production,hope to offer a theoretical basis for industrialized mass production.
作者 孙浩轩 周卫强 杨硕 彭超 陈博 王晓健 李义 佟毅 SUN Hao-xuan;ZHOU Wei-qiang;YANG Shuo;PENG Chao;CHEN Bo;WANG Xiao-jian;LI Yi;TONG Yi(Nutrition and Health Research Institute,COFCO,Beijing 102209,China;Beijing Key Laboratory of Nutrition,Health and Food Safety,Beijing 102209,China;Beijing Engineering Laboratory for Geriatric Nutrition Food Research,Beijing 102209,China;COFCO Biochemical Energy(Longjiang)Co.,Ltd.,Qiqihar Heilongjiang 161100,China;COFCO Biochemical Co.,Ltd.,Bengbu Anhui 233010,China;National Engineering Research Center of Corn Deep Processing,Changchun Jilin 130033,China)
出处 《食品与发酵科技》 CAS 2021年第5期91-96,112,共7页 Food and Fermentation Science & Technology
关键词 L-乳酸 微生物发酵 光学纯度 L-lactic acid microbial fermentation optical purity
作者简介 孙浩轩(1996-),男,本科。研究方向:发酵工程;通信作者:佟毅。
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