摘要
目的评估四变量评分在筛查阻塞性睡眠呼吸暂停综合征(OSAS)中应用价值。方法回顾性分析477例可疑OSAS患者临床资料及四变量、STOP问卷、STOP-Bang问卷(SBQ)、柏林问卷(BQ)评分,根据呼吸暂停低通气指数(AHI)分为正常(AHI<5次/h)及轻度(5≤AHI<15次/h)、中度(15≤AHI<30次/h)和重度OSAS(AHI≥30次/h)。结果在AHI=5时,四变量评分ROC曲线下面积(AUC)最大(0.747,P<0.01),STOP问卷AUC最小(0.665,P<0.01)。四变量评分以11分为临界值,四变量评分敏感度(0.828)>SBQ(0.765)>STOP(0.714)>BQ最低(0.602)。结论四变量评分临界值为11分时,有较高敏感度和阴性预测值,在筛查OSAS中明显优于SBQ、STOP、BQ问卷。
Objective To evaluate the value of four-variable scores in obstructive sleep apnea syndrome(OSAS).Methods Clinical data,four-variable scores,STOP questionnaire,STOP-Bang questionnaire(SBQ),and Berlin questionnaire(BQ)were retrospectively analyze in 477 patients with suspected OSAS.Based on apnea hypopnea index(AHI),these patients were divided into normal(AHI<5 times/h),mild(5≤AHI<15 times/h),moderate(15≤AHI<30 times),and severe(AHI≥30 times/h)OSAS groups.Results If AHI was 5,the area under curve(AUC)was maximal for four variable scores(0.747,P<0.01),and minimal(0.665,P<0.01)for STOP questionnaire.If cut off was 11,the sensitivity was 0.828 for four-variable scores,0.765 for SBQ,0.714 for STOP,and 0.602 for BQ in descending order.Conclusion The sensitivity and negative predictive value of four-variable scores are higher with cut off of 11,which is superior to SBQ,STOP,and BQ in screening OSAS.
作者
何啟忠
朱金儒
郑珍珍
曾煜
刘旺
陈日垦
彭敏
洪城
成俊芬
HE Qi-zhong;ZHU Jin-ru;ZHENG Zhen-zhen;ZENG Yu;LIU Wang;CHEN Ri-ken;PENG Min;HONG Cheng;CHENG Jun-fen(Department of Respiratory Medicine,Second Affiliated Hospital of Guangdong Medi‐cal University,Zhanjiang 524000,China;Department of Respiratory and Critical Care Medicine,First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510120,China)
出处
《广东医科大学学报》
2021年第5期600-604,共5页
Journal of Guangdong Medical University
基金
广东医科大学科研基金(No.GDMUM201836,No.GDMUM2019043)。
作者简介
何啟忠(1982‒),男,学士,主治医师;通信作者:洪城,(1974‒),男,博士,副主任医师,E-mail:gy⁃fyyhc@126.com。
