摘要
胞外囊泡是由细胞分泌的纳米级囊泡,包括外泌体和微囊泡。它可以通过多种机制被受体细胞摄取,传递细胞间信息,调控细胞的生物学功能。有研究发现,胞外囊泡与自身免疫性疾病、色素性疾病、肿瘤及皮肤创伤愈合等密切相关,在各种生理和病理过程中发挥着重要的生物学作用。本文综述胞外囊泡与皮肤科相关研究进展。
Extracellular vesicles are nanoscale vesicles secreted by cells,including exosomes and microvesicles.They can be ingested by recipient cells through a variety of mechanisms,transmitting intercellular information and regulating biological functions of recipient cells.Studies have found that extracellular vesicles are closely related to skin diseases,such as autoimmune diseases,pigmented diseases,tumors and wound healing,,and play important biological roles in various physiological and pathological processes.This review summarizes updates on extracellular vesicles in dermatology.
作者
陈伟
谢恒
李利
Chen Wei;Xie Heng;Li Li(Department of Medical Cosmetology,Chengdu Second People fs Hospital,Chengdu 610017,China;Department of Medical Cosmetology,Guangdong Provincial Dermatology Hospital^Guangzhou 510095,China;Department of Dermatology,West China Hospital,Sichuan University,Chengdu 610041,China)
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2021年第10期910-914,共5页
Chinese Journal of Dermatology
关键词
外泌体
胞外囊泡
微囊泡
皮肤疾病
Exosomes
Extracellular vesicles
Microvesicles
Skin diseases
作者简介
通信作者:李利,Email:hxskin2017@qq.com。
