摘要
Epidemiological data show that the incidence rate of cholangiocarcinoma(CCA)has been increasing over the past 20 years.Due to its concealment of clinical manifestations,most patients are diagnosed with CCA at a late stage.On this premise,this review not only discusses the research progress related to CCA diagnosis,but also focuses on the concept of circulating tumor cell(CTC),its evaluation value,application,and prospects for the early diagnosis of extrahepatic cholangiocarcinoma.
基金
This work was supported by Baoding Technology Program(project number:2041ZF084).
作者简介
Corresponding author:Ying Xiong,xy_spring@163.com,These authors contributed equally to this work;Corresponding author:Jinku Zhang,zjkblk@sina.com,These authors contributed equally to this work。