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分析微创腹腔镜剔除术治疗子宫肌瘤的疗效及对免疫功能的影响 被引量:2

Analysis of the efficacy of minimally invasive laparoscopic excision in the treatment of uterine fibroids and its influence on immune function
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摘要 目的分析微创腹腔镜剔除术治疗子宫肌瘤的疗效和对免疫功能的影响。方法80例行手术治疗的子宫肌瘤患者,按照随机对照原则分为对照组及观察组,每组40例。对照组采用传统开腹子宫肌瘤剔除术治疗,观察组采用微创腹腔镜剔除术治疗。对比两组手术成功率、随访2年复发率、免疫功能、并发症发生率。结果两组患者均手术成功,成功率为100%;随访2年,观察组复发率2.50%低于对照组的5.00%,但差异无统计学意义(P>0.05)。术后3 d,两组患者CD3+和CD4+水平均低于术前,但观察组CD3+和CD4+水平高于对照组,差异有统计学意义(P<0.05)。观察组治疗后并发症发生率2.50%(1/40)显著低于对照组的20.00%(8/40),差异有统计学意义(P<0.05)。结论对子宫肌瘤患者行微创腹腔镜剔除术治疗的疗效与开腹术效果相近,但对于患者免疫功能影响较小,且安全性较高。 Objective To analyze the efficacy of minimally invasive laparoscopic excision in the treatment of uterine fibroids and its influence on immune function.Methods A total of 80 patients with uterine fibroids were randomly divided into control group and observation group,with 40 cases in each group.The control group was treated with traditional open myomectomy,and the observation group was treated with minimally invasive laparoscopic excision.The surgical success rate,recurrence rate after 2 years of follow-up,immune function,and occurrence of complications were compared between the two groups.Results The operation was successful in both groups,and the success rate was 100%.After 2 years of follow-up,the recurrence rate 2.50%of the observation group was lower than 5.00%of the control group,but the difference was not statistically significant(P>0.05).3 d after operation,the CD3+and CD4+of the two groups were lower than those before operation,but the observation group was higher than the control group.All the difference was statistically significant(P<0.05).The incidence of complications 2.50%(1/40)of the observation group was significantly lower than 20.00%(8/40)of the control group,and the difference was statistically significant(P<0.05).Conclusion The efficacy of minimally invasive laparoscopic excision is similar to that of myomectomy,but minimally invasive laparoscopic excision has less impact on the immune function of patients with uterine fibroids,and has higher safety.
作者 王亚尼 WANG Ya-ni(Department of Obstetrics and Gynecology,People’s Hospital of Qingyuan Manchu Autonomous County,Fushun 113300,China)
出处 《中国实用医药》 2021年第26期60-62,共3页 China Practical Medicine
关键词 微创腹腔镜剔除术 子宫肌瘤 近远期疗效 免疫功能 Minimally invasive laparoscopic excision Uterine fibroids Short-term and long-term efficacy Immune function
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