摘要
目的分析氨茶碱与多索茶碱治疗慢性阻塞性肺疾病的效果。方法选择2019年5月—2020年5月期间74例慢性阻塞性肺疾病患者作为研究对象,其中观察者进行多索茶碱治疗,对照组进行茶碱治疗,将患者的治疗效果、不良反应发生率、肺功能指标、观察指标进行对比。结果结果发现,观察者治疗效果高于对照组,不良反应发生率低于观察组,对比差异有统计学意义(P<0.05)。观察组的FEV1、FVC、FEV1/FVC等肺功能指标分别为(1.69±0.23)L、(2.55±0.68)L、(72.38±5.12)%,均优于对照组,差异有统计学意义(P<0.05)。观察组的住院时间、咳嗽好转时间、肺啰音消失时间等观察指标分别为(14.42±2.12)d、(1.81±0.35)d、(2.56±1.74)d,均优于对照组,差异有统计学意义(P<0.05)。结论多索茶碱治疗慢性阻塞性肺疾病的效果更高。
Objective To analyze the effect of aminophylline and doxofylline in the treatment of chronic obstructive pulmonary disease.Methods A total of 74 patients with chronic obstructive pulmonary disease from May 2019 to May 2020 were selected as the study subjects.The observer was treated with doxofylline,and the control group was treated with theophylline.The therapeutic effect,incidence of adverse reactions,pulmonary function indexes and observation indexes of the patients were compared.Results The results showed that the therapeutic effect of the observer was higher than that of the control group,and the incidence of adverse reactions was lower than that of the observation group,with statistical significance(P<0.05).The lung function indexes of FEV1,FVC,FEV1/FVC in the observation group were(1.69±0.23)L,(2.55±0.68)L and(72.38±5.12)%,respectively,which were better than those in the control group,with statistical significance(P<0.05).The length of hospital stay,cough recovery time and lung rales disappearance time in the observation group were(14.42±2.12)d,(1.81±0.35)d and(2.56±1.74)d,respectively,which were better than those in the control group,with statistical significance(P<0.05).Conclusion Doxofylline is more effective in treating chronic obstructive pulmonary disease.
作者
卢刚
LU Gang(Department of Respiratory Medicine,The Third Hospital of Ezhou City,Ezhou Hubei 436000,China)
出处
《中国继续医学教育》
2021年第27期153-156,共4页
China Continuing Medical Education
关键词
氨茶碱
多索茶碱
慢性阻塞性肺疾病
效果
对比
肺功能
aminophylline
doxofylline
chronic obstructive pulmonary disease
effect
comparison
lung function
