摘要
目的:探讨稽留流产发病的危险因素,为其防治干预措施提供依据。方法:选取2018年3月-2019年10月于本院诊断为稽留流产的137例患者为试验组,选择同期正常妊娠孕妇101例为对照组。采用统一的信息问卷调查表对所有患者进行问卷调查,比较两组男女双方的基线资料、生活习惯及心理状态,多因素logistic回归分析导致稽留流产发病的相关危险因素。结果:两组女方的年龄、BMI、学历、流产史、孕期饮酒史及焦虑评分比较,差异均无统计学意义(P>0.05);两组女方的居住地、孕期被动吸烟史、环境毒物接触史、孕期生殖道感染、孕期补充叶酸、孕前半年烫染发、抑郁评分比较,差异均有统计学意义(P<0.05)。两组男方吸烟、饮酒、环境毒物接触史比较,差异均有统计学意义(P<0.05)。logistic回归分析结果显示:女方焦虑、抑郁和男方饮酒均是稽留流产发病的独立危险因素(P<0.05),而女方居住城镇为稽留流产发病的保护性因素(P<0.05)。结论:女方毒物环境因素、感染因素、心理应激因素以及男方吸烟、饮酒史可增加稽留流产发病风险,应有针对性对其加强干预,降低稽留流产发病率。
Objective:To explore the risk factors of missed abortion and to provide evidence for its prevention and intervention measures.Method:A total of 137 patients diagnosed as missed abortions in our hospital from March 2018 to October 2019 were selected as the experimental group,and 101 normal pregnant women during the same period were selected as the control group.A unified information questionnaire was used to conduct a questionnaire survey on all patients,and the baseline data,living habits and psychological states of both male and female in the two groups were compared.Multivariate logistic regression was used to analyze the risk factors leading to missed abortion.Result:Comparison of age,BMI,educational background,history of abortion,history of alcohol consumption during pregnancy and anxiety scores between the female of two groups,there were no statistical significance between the two groups (P>0.05).Comparison of residence,history of passive smoking during pregnancy,history of exposure to environmental toxicants,reproductive tract infection during pregnancy,folic acid supplementation during pregnancy,hair ironing and dyeing in the first six months of pregnancy and depression scores between the female of two groups,the differences were statistically significant (P<0.05).Comparison of smoking,drinking and exposure to environmental toxins between the male of two groups,the differences were statistically significant (P<0.05).logistic regression analysis showed that female anxiety,depression and male drinking were independent risk factors for the incidence of missed abortion (P<0.05),while the town where the female lived was a protective factor for the incidence of missed abortion (P<0.05).Conclusion:Toxic environmental factors,infectious factors and psychological stress factors of female,and the male’s smoking and drinking history can increase the risk of missed abortion.Therefore,targeted intervention should be strengthened to reduce the incidence of missed abortion.
作者
孙博
倪娜
朱倩
SUN Bo;NI Na;ZHU Qian(Nanjing Jiangning Hospital,Nanjing 211100,China)
出处
《中国医学创新》
CAS
2021年第22期182-185,共4页
Medical Innovation of China
基金
南京医科大学康达学院科研发展基金课题(KD2017KYJJYB018)。
关键词
稽留流产
危险因素
调查
Missed abortion
Risk factors
Investigation
作者简介
通信作者:孙博。
