摘要
目的探讨高频超声半定量评分在伴环形钙化甲状腺结节良恶性诊断中的应用价值。方法选取114例伴环形钙化甲状腺结节患者为研究对象,均行超声检查、高频超声半定量评分计算、术后病理检查。根据术后病理检查结果其分为良性组、恶性组,比较两组的钙化环征象。采用受试者工作特征曲线(ROC)分析高频超声半定量评分诊断恶性伴环形钙化甲状腺结节的效能。结果恶性组钙化环厚度不均匀、连续性中断、位于结节内部患者占比显著高于良性组(P<0.05)。伴环形钙化甲状腺结节的高频超声半定量评分为1~8分,其中良性组高频超声半定量评分显著低于恶性组(P<0.05)。高频超声半定量评分≤3分的恶性率为4.8%,4~5分的恶性率为27.8%,6~8分的恶性率为90.5%。ROC曲线显示,高频超声半定量评分>4分时,诊断恶性伴环形甲状腺结节的灵敏度为80.00%,明显高于钙化环厚度不均匀、连续性中断、位于结节内部等单一征象(P<0.05)。结论高频超声半定量评分在伴环形甲状腺结节良恶性诊断中具有一定的应用价值,评分≥6分提示结节恶性风险极高,应引起高度重视。
Objective To evaluate the application value of high-frequency ultrasound semi quantitative score in the diagnosis of benign and malignant thyroid nodules with annular calcification.Methods A total of 114 patients with thyroid nodules and annular calcification were selected as the study subjects,and all patients underwent ultrasonography,high-frequency ultrasound semi quantitative score calculation and postoperative pathological examination.According to the results of postoperative pathological examination,the patients were divided into benign group and malignant group,and the signs of calcified ring were compared between the two groups.Receiver operating characteristic curve(ROC)was used to analyze the efficacy of high-frequency ultrasound semi quantitative score in the diagnosis of malignant thyroid nodules with annular calcification.Results The proportion of patients with uneven thickness,interrupted continuity and located inside the nodule of calcified ring in the malignant group were significantly higher than those in the benign group(P<0.05).The high-frequency ultrasound semi quantitative score in thyroid nodules with annular calcification was 1-8,and the high-frequency ultrasound semi quantitative score in the benign group was significantly lower than that in the malignant group(P<0.05).The malignant rate of high-frequency ultrasound with semi quantitative score≤3 was 4.8%,that of 4-5 was 27.8%,and that of 6-8 was 90.5%.ROC curve showed that when the high-frequency ultrasound with semi quantitative score>4,the sensitivity in the diagnosis of malignant thyroid nodules with annular calcification was 80.00%,which was significantly higher than that of single signs such as uneven thickness,interrupted continuity and located inside the nodule of calcified ring(P<0.05).Conclusion High-frequency ultrasound with semi quantitative score has certain application value in the diagnosis of benign and malignant thyroid nodules with annular calcification,the score≥6 indicates that the risk of malignant nodules is very high,which should be paid great attention to.
作者
南格利
宋林科
程颢
NAN Geli;SONG Linke;CHENG Hao(Xi'an Gaoxin Hospital,Xi'an 710075;the Fourth People's Hospital of Shaanxi,Xi'an 710043;Shaanxi Provincial Cancer Hospital Affiliated to Xi'an Jiaotong University Health Science Center,Xi'an 710061,China)
出处
《临床医学研究与实践》
2021年第26期116-118,共3页
Clinical Research and Practice
基金
陕西省重点研发计划项目(No.2020SF-163)。
关键词
伴环形钙化甲状腺结节
高频超声
半定量评分
良恶性
thyroid nodules with annular calcification
high-frequency ultrasound
semi quantitative score
benign and malignant
作者简介
南格利(1978-),女,汉族,陕西咸阳人,主治医师,学士。研究方向:心脏、血管疾病;通讯作者:宋林科,E-mail:linke6789@126.com.
