摘要
目的分析2016—2019年广州市无偿献血者酶联免疫检测(ELISA)情况。方法对广州血液中心2016—2019年的无偿献血者进行乙肝表面抗原(HBsAg)、丙型肝炎病毒(HCV)抗体、人类免疫缺陷病毒(HIV)抗体及梅毒螺旋体(TP)抗体的ELISA检测。结果2016—2019年HBsAg阳性9560例(0.678%)、HCV抗体阳性2255例(0.160%)、HIV抗体阳性1479例(0.105%)、TP抗体阳性4002例(0.284%);2016—2019年HBsAg阳性者合并TP抗体阳性率最高,且阳性率呈逐年下降趋势(χ^(2)=7.997,P=0.046)。HCV抗体阳性者合并TP抗体阳性率呈现逐年下降趋势,差异有统计学意义(χ^(2)=8.097,P=0.044)。2016—2019年HCV抗体阳性者合并TP抗体阳性率均高于合并HIV抗体阳性率,且2016、2017年差异有统计学意义(χ^(2)=17.406,P<0.05;χ^(2)=4.340,P=0.037)。结论在对HBsAg、HCV抗体、HIV抗体及TP抗体的检测中,广州市无偿献血者HBsAg阳性率最高;HBsAg阳性者合并TP抗体阳性率最高,并呈现逐年下降的趋势;HCV抗体阳性者合并TP抗体阳性率高于HIV抗体阳性者。
Objective To analyze theenzyme-linked immunosorbent assay(ELISA)for voluntary blood donors in Guangzhou from 2016 to 2019.Methods ELISA tests for hepatitis B surface antigen(HBsAg),hepatitis C virus(HCV)antibody,human immunodeficiency virus(HIV)antibody and treponema pallidum(TP)antibody were performed on voluntary blood donors in Guangzhou Blood Center from 2016 to 2019.Results From 2016 to 2019,9560 cases(0.678%)were positive for HBsAg,2255 cases(0.160%)were positive for HCV antibodies,1479 cases(0.105%)were positive for HIV antibodies,and 4002 cases(0.284%)were positive for TP antibodies.From 2016 to 2019,the rate of TP antibody positive in HBsAg positive patients was the highest,and the positive rate showed a decreasing trend year by year(χ^(2)=7.997,P=0.046).Meanwhile,the rate of TP antibody positive in HCV antibody positive patients showed a decreasing trend year by year,with statistically significant difference(χ^(2)=8.097,P=0.044).The rate of TP antibody positive in HCV antibody positive patients was higher than that of HIV antibody positive in HCV antibody positive patients from 2016 to 2019,and the difference between 2016 and 2017 were statistically significant(χ^(2)=17.406,P<0.05;χ^(2)=4.340,P=0.037).Conclusion In the testing of HBsAg,HCV antibodies,HIV antibodies and TP antibodies,the rate of HBsAg positiveis the highest in voluntary blood donors in Guangzhou.The rate of TP antibody positive in HBsAg positive patients is the highest and it shows a decreasing trend year by year.The rate of TP antibody positive in HCV antibody positive patients is higher than that of HIV antibody positive in HCV antibody positive patients.
作者
蓝岚茵
郑剑婷
芦曦
LAN Lanyin;ZHENG Jianting;LU Xi(Guangzhou Blood Center,Guangzhou Key Laboratory of Medicine(Key Laboratory of Blood Safety),Guangdong,Guangzhou 510095,China)
出处
《中国医药科学》
2021年第14期159-161,169,共4页
China Medicine And Pharmacy
基金
广东省医学科研基金立项项目(B2017109)。
关键词
乙肝表面抗原
丙型肝炎病毒
人类免疫缺陷病毒
梅毒螺旋体
Hepatitis B surface antigen
Hepatitis C virus
Human immunodef iciency virus
Treponema pallidum
