摘要
目的:探讨体重管理对超重及肥胖多囊卵巢综合征(PCOS)患者代谢指标及妊娠结局的影响。方法:选取2018年1月-2019年12月本院收治的超重及肥胖PCOS患者80例分为两组,对照组行常规治疗,观察组在对照组基础上进行体重管理。比较两组卵巢体积、腰臀比、体质指数(BMI)、睾酮(T)、促卵泡素(FSH)、黄体生成素(LH)、雌二醇(E2)水平、空腹胰岛素(FINS)、餐后2h血糖(2hPBG)、空腹血糖(FBG)、胰岛素抵抗指数(HOMA-IR)情况、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP),排卵、月经恢复及妊娠情况。结果:治疗后观察组卵巢体积(7.6±1.7 cm^(3))、腰臀比(0.8±0.1)、BMI(23.8±2.3 kg/m^(2)),T、FSH、LH、E2、FINS、2hPBG、FBG、HOMA-IR,IL-6、TNF-α、CRP均小于对照组(均P<0.05);排卵(97.5%)、月经恢复(72.5%)、妊娠率(97.5%)大于对照组(P<0.05)。结论:超重及肥胖PCOS患者治疗中加强体重饮食管理效果较好,值得应用。
Objective:To investigate the influence of weight management for overweight or obese women with polycystic ovary syndrome(PCOS)on their metabolic indexes and pregnancy outcomes.Methods:80 overweight and obese women with PCOS were selected and were divided into two groups by random number table method from January 2018 to December 2019.The women in the control group were given routinely management,and the women in the study group were given weight management except to the routinely management.The ovarian volume,waist hip ratio,body mass index,the levels testosterone(T),follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E2),fasting insulin(FINS),2 h postprandial blood glucose(2hPBG),and fasting blood glucose(FBG),and interleukin 6(IL-6),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),the value of insulin resistance index(HOMA-IR),and the situations of ovulation,menstruation recovery,and pregnancies of the women were compared between the two groups.Results:The ovarian volume(7.6±1.7 cm^(3)),waist-hip ratio(0.8±0.1),body mass index(23.8±2.3 kg/m^(2)),the levels of T,FSH,LH,E2,FINS,2hPBG,FBG,IL-6,TNF-α,and CRP,and the HOMA-IR value of the women in the study group were significant less than those of the women in the control group(P<0.05).The rates of ovulation(72.5%),menstrual recovery(80.0%),and pregnancy(97.5%)of the women in the study group were significant higher than those of the women in the control group(P<0.05).Conclusion:Weight and diet managements for overweight or obese women with PCOS has better effectiveness,which is worthy of application.
作者
黄芳
赵花
彭顺英
HUANG Fang;ZHAO Hua;PENG Shunying(The First People's Hospital of Zhaoqing, Guangdong Province,526060)
出处
《中国计划生育学杂志》
2021年第7期1515-1518,共4页
Chinese Journal of Family Planning
关键词
多囊卵巢综合征
超重、肥胖
体重管理
代谢指标
妊娠结局
Polycystic ovary syndrome
Overweight
Obesity
Weight management
Metabolic index
Pregnancy outcomes
