摘要
目的:比较丙泊酚分别复合纳布啡、地佐辛、舒芬太尼用于无痛人工流产术的临床效果。方法:选取2019年1月-2020年6月拟在本院自愿行无痛人工流产术的早孕妇女156例,按随机数字表法分为3组各52例,A组丙泊酚复合地佐辛,B组丙泊酚复合纳布啡,C组丙泊酚复合舒芬太尼。比较各组手术不同时间收缩压(SBP)、舒张压(DBP)、心率(HR)、血氧饱和度(SpO2)以及麻醉情况和不良反应。结果:给药前、睫毛反应消失时,B组SBP、DBP、SpO2均大于A组和C组(P<0.05)。B组丙泊酚用量(113.7±10.3mg)、苏醒时间(3.35±0.4min)少于A组(132.2±21.5mg、7.1±1.3 min)和C组(129.4±15.7mg、5.8±0.9min)(P<0.05),B组不良反应总发生率(19.2%)低于A组(57.7%)和C组(53.9%)(P<0.05)。结论:丙泊酚复合纳布啡的麻醉有效性、安全性均优于丙泊酚复合地佐辛或舒芬太尼。
Objective:To compare the clinical effect of propofol combined with nalbuphine,dezocine,or sufentanil for analgesia in painless induced abortion.Methods:From January 2019 to June 2020,156 pregnant women who wanted painless induced abortion during the first trimester of pregnancy were selected and were divided into three groups by random number table,which included group A(52 women accepted propofol combined with dezocine for analgesia),group B(52 women accepted propofol combined with nalbuphine for analgesia),and group C(52 women accepted propofol combined with sufentanil for analgesia).The values of systolic blood pressure(SBP),diastolic blood pressure(DBP),heart rate(HR),and blood oxygen saturation(SpO2)of the women at different times,anesthesia effect,and adverse reactions rate of the women were compared among the three groups.Results:The values of SBP,DBP,and SpO2 of the women before administration of anesthesia drug and when eyelash reaction disappeared in group B were significant higher than those of the women in group A and group C(P<0.05).The dosage of propofol(113.7±10.3mg)and awaken time(3.35±0.4min)of the women in group B were significant less than those(132.2±21.5mg and 7.1±1.3 min)of the women in group A,and those(129.4±15.7mg and 5.8±0.9min)in group C(P<0.05).The total incidence of adverse reaction(19.2%)of the women in group B was significant lower than that(57.7%)of the women in group A,and that(53.9%)of the women in group C(P<0.05).Conclusion:The efficacy and safety of propofol combined with nalbuphine for anesthesia in painless induced abortion are better than those of propofol combined with dezocine or sufentanil.
作者
费菲
黄晓辰
杨佳
FEI Fei;HUANG Xiaochen;YANG Jia(The Second People's Hospital of Huai 'an, Jiangsu Province, 223001;Nanjing Jiangning Hospital;Huai 'an Hospital of Traditional Chinese Medicine)
出处
《中国计划生育学杂志》
2021年第7期1356-1359,共4页
Chinese Journal of Family Planning
关键词
无痛人工流产术
麻醉
镇痛
丙泊酚
纳布啡
地佐辛
舒芬太尼
Painless induced abortion
Anesthesia
Analgesia
Propofol
Nalbuphine
Dezocine
Sufentanil
作者简介
通信作者:杨佳,1150147010@qq.com。
