摘要
BACKGROUND Multiple primary cancer refers to more than one synchronous or sequential cancer in the same individual.Multiple primary cancer always presents as solid cancer or acute myeloid leukemia(AML)secondary to lymphoma.Here,we report a rare case of secondary peripheral T-cell lymphoma and AML after Burkitt lymphoma treatment.CASE SUMMARY A 54-year-old female patient was admitted to our hospital complaining of edema on her left lower limb.Physical examination revealed multiple superficial lymphadenectasis on her neck and pelvis.Color ultrasonography examination showed multiple uterine fibroids and a solid mass at the lower left side of the abdomen.Pathological biopsy revealed Burkitt lymphoma.After three hyper-CVAD(A+B)regimens,she achieved complete remission.Two years later,lymphadenectasis reoccurred.A relevant biopsy confirmed the diagnosis of peripheral T-cell lymphoma,which was accompanied by gastrointestinal invasion and hemocytopenia.Meanwhile,bone marrow examination revealed AML.On the second day of scheduled treatment,she developed gastrointestinal bleeding,peptic ulcers,and hemorrhagic shock and was critically ill.She was then discharged from the hospital due to financial concerns.CONCLUSION This is the first report of secondary peripheral T-cell lymphoma and AML after Burkitt lymphoma treatment with heterochronous and synchronal multiple primary cancers.
基金
Medical and Health Research Project of Hainan Province,No.20A200013.
作者简介
Li Huang,ORCID number:0000-0002-7012-8048;Can Meng,ORCID number:0000-0002-7774-6316;Dan Liu,ORCID number:0000-0002-6290-6153;Corresponding author:Xiang-Jun Fu,Department of Hematology,Hainan General Hospital,Hainan Affiliated Hospital of Hainan Medical University,No.19 Xiuhua Road,Xiuying District,Haikou 570311,Hainan Province,China.78318742@qq.com,ORCID number:0000-0001-8077-6201.
