摘要
银屑病是以红色丘疹或斑块上覆盖多层银白色鳞屑为特征的慢性炎症性皮肤病,易复发、难根治。有研究表明,皮肤和肠道菌群与银屑病密切相关。益生菌可以通过调节肠道菌群、增强肠道功能来减少全身的炎症反应,对银屑病的预防和治疗有一定作用。该文论述肠道、皮肤微生物与银屑病关系以及益生菌治疗银屑病的相关机制和疗效,挖掘益生菌在防治银屑病中的潜力,为银屑病的临床治疗提供新的思路。
Psoriasis is a chronic inflammatory skin disease characterized by red papules or plaques covered with layers of silvery scales,with frequent recurrence and difficulties in radical treatment.Studies have shown that skin and gut microbiota are closely associated with psoriasis.Probiotics can prevent and treat psoriasis by regulating gut microbiota,enhancing gut function,and thus reducing systemic inflammatory response.This article expounds the association of the intestinal tract and skin microorganisms with psoriasis and the mechanism and effect of probiotics in the treatment of psoriasis,so as to explore the potential of probiotics in the prevention and treatment of psoriasis and provide new ideas for the clinical treatment of psoriasis.
作者
张会健
母丹
黎昌强
ZHANG Hui-jian;MU Dan;LI Chang-qiang(College of Clinical Medicine,Southwest Medical University,Luzhou 646000,China;Department of Dermatol-ogy,the Affiliated Hospital of Southwest Medical University,Luzhou 646000,China)
出处
《西南医科大学学报》
2021年第4期408-411,共4页
Journal of Southwest Medical University
基金
四川省大学生创新创业训练计划项目(S201910764133)。
关键词
银屑病
肠道菌群
皮肤微生物
益生菌
Psoriasis
Gut microbiota
Skin microorganism
Probiotics
作者简介
第一作者:张会健,本科生。;通信作者:黎昌强,主任医师,博士。E-mail:lcq-1973@163.com。
