摘要
目的:观察限制性输血治疗上消化道出血患者的临床效果。方法:选取86例上消化道出血患者作为研究对象,按照随机数字表法分为对照组与观察组各43例。对照组接受常规输血治疗,观察组接受限制性输血治疗。比较两组治疗前后血常规指标[血细胞比容(Hct)、血红蛋白(Hb)、血小板计数(PLT)]水平、凝血指标[部分凝血活酶时间(APTT)、凝血酶原时间(PT)]水平,治疗期间输血量、止血时间和临床疗效,以及不良反应发生率。结果:治疗后,观察组Hb、Hct和PLT水平均高于对照组,APTT和PT水平均低于对照组,差异有统计学意义(P<0.05);观察组治疗期间输血量少于对照组,止血时间短于对照组,差异均有统计学意义(P<0.05);两组治疗总有效率比较,差异无统计学意义(P>0.05);观察组不良反应发生率为4.65%,低于对照组的23.26%,差异有统计学意义(P<0.05)。结论:限制性输血治疗上消化道出血患者,可提高血常规指标水平,降低凝血指标水平、输血量和不良反应发生率,缩短止血时间,其效果优于常规输血治疗。
Objective:To observe application effects of restrictive blood transfusion in patients with upper gastrointestinal bleeding.Methods:86 patients with upper gastrointestinal bleeding were selected as the research objects,and were divided into control group and observation group according to the random number table method,43 cases in each group.The control group received conventional blood transfusion therapy,while the observation group received restrictive blood transfusion therapy.The blood routine indexes[hematocrit(Hct),hemoglobin(Hb),platelet count(PLT)]levels and the coagulation indexes[partial thromboplastin time(APTT),prothrombin time(PT)]levels before and after the treatment,the blood transfusion level during the treatment,the time to hemostasis,the clinical efficacy,and incidence of adverse reactions were compared between the two groups.Results:After the treatment,the Hb,Hct and PLT levels in the observation group were higher than those in the control group;the APTT and PT levels were lower than those in the control group;and the differences were statistically significant(P<0.05).The blood transfusion volume in the observation group during the treatment was lower than that in the control group;the time to hemostasis was shorter than that in the control group;and the differences were statistically significant(P<0.05).There was no statistically significant difference in the total effective rate of treatment between the two groups(P>0.05).The incidence of adverse reactions in the observation group was 4.65%,which was lower than 23.26%in the control group,and the difference was statistically significant(P<0.05).Conclusions:Restrictive blood transfusion therapy for the patients with upper gastrointestinal bleeding can improve the blood routine index levels,reduce the blood coagulation index levels,the blood transfusion volume and the incidence of adverse reactions,and shorten the time to hemostasis.Moreover,it is superior to conventional blood transfusion therapy.
作者
梁振国
LIANG Zhenguo(Department of Blood Transfusion of Xincai County People’s Hospital,Zhumadian 463500 Henan,China)
出处
《中国民康医学》
2021年第13期7-9,共3页
Medical Journal of Chinese People’s Health
关键词
上消化道出血
限制性输血
止血
凝血
输血量
不良反应
Upper gastrointestinal bleeding
Restrictive blood transfusion
Hemostasis
Coagulation
Blood transfusion volume
Adverse reaction
作者简介
梁振国(1976.10-),男,汉族,河南驻马店人,本科,副主任技师,研究方向:输血治疗。
