摘要
肥厚型梗阻性心肌病(hypertrophic obstructive cardiomyopathy,HOCM)是肥厚型心肌病的一类亚型,因肥厚的室间隔造成左心室梗阻而得名。目前的治疗方案包括药物治疗、介入治疗和手术治疗。部分HOCM患者药物治疗效果不佳或不耐受,需要非药物方法治疗。中国医学科学院阜外医院心内科已完成了近500例HOCM经皮室间隔心肌消融术治疗,积累了一定的经验,因此制定了HOCM经皮室间隔心肌消融术临床操作规范,主要包括适应证、禁忌证、操作要点及术后监测等,并提出了并发症的处理策略。建议全国心内科医师高度重视并开展此项检查和治疗技术,以提高我国HOCM经皮室间隔心肌消融术治疗水平。
Hypertrophic obstructive cardiomyopathy(HOCM)is defined as a primary,sometimes familial and genetically fixed myocardial hypertrophy.In addition to standard therapy of symptomatic patients(medical treatment with beta blockers and calcium-antagonists of verapamil-type as well as surgical myotomy/myectomy)percutaneous transluminal septal myocardial ablation(PTSMA)by alcohol-induced septal branch occlusion has been recommended.Fuwai Hospital has completed nearly 500 cases of PTSMA.Therefore,the clinical standards and specifications of PTSMA have been formulated to improve the treatment level of HOCM.
作者
罗晓亮
袁建松
杨伟宪
LUO Xiao-liang;YUAN Jian-song;YANG Wei-xian(Center for Coronary Heart Disease,State Key Laboratory of Cardiovascular Disease,Fuwai Hospital,National Center for Cardiovascular Disease,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China)
出处
《中国分子心脏病学杂志》
CAS
2021年第3期3913-3917,共5页
Molecular Cardiology of China
基金
北京协和医学院“双一流”临床医学学科建设子项目(2019E-XK04-02)。
关键词
肥厚型梗阻性心肌病
经皮室间隔心肌消融术
Hypertrophic obstructive cardiomyopathy
Percutaneous transluminal septal myocardial ablation
作者简介
通信作者:杨伟宪,Email:wxyang2009@sina.com。
