摘要
目的研究使用雷贝拉唑与雷尼替丁对非糜烂性胃食管反流病进行治疗的临床效果。方法将2018年3月至2019年3月到我院治疗的72例非糜烂性胃食管反流病患者分为观察组与对照组,每组36例。在常规治疗方法的基础上,对照组患者通过雷尼替丁进行治疗,观察组通过雷贝拉唑治疗。比较两组治疗的效果。结果观察组病情控制有效率(88.89%)明显高于对照组(69.44%)(P<0.05)。观察组的复发率[3.13%(1/32)]明显低于对照组[32.00%(8/25)](P<0.05)。观察组并发症发生率(8.33%)明显低于对照组(30.56%)(P<0.05)。观察组治疗后的QOL评分明显高于对照组(P<0.05)。结论对非糜烂性胃食管反流病患者在常规治疗的同时服用雷贝拉唑所取得的疗效明显比服用雷尼替丁更好,可有效提升患者对病情的总体控制效率,降低复发的概率和并发症出现的概率,能提升患者的整体生活质量。
Objective To evaluate the clinical effects of rabeprazole and ranitidine on non-erosive gastroesophageal reflux disease.Methods The 72 patients with non-erosive gastroesophageal reflux disease who came to our hospital for treatment from March 2018 to March 2019 were divided into observation group and control group,with the same number of 36 cases.The two groups of patients were treated with conventional treatment methods,while the control group was treated with ranitidine,and the observation group was treated with rabeprazole.The effects of the two groups were compared.Results The effective rate of disease control in the observation group(88.89%)was significantly higher than that of the control group(69.44%)(P<0.05).The recurrence rate of the observation group[3.13%(1/32)]was significantly lower than that of the control group[32.00%(8/25)](P<0.05).The incidence of complications in the observation group(8.33%)was significantly lower than that in the control group(30.56%)(P<0.05).The QOL score of the observation group after treatment was significantly higher than that of the control group(P<0.05).Conclusion For patients with non-erosive gastroesophageal reflux disease,taking rabeprazole at the same time as conventional treatment has significantly better curative effect than taking ranitidine,which can effectively improve the patient's overall control efficiency of the disease and reduce the probability of recurrence.The probability of complications can improve the overall quality of life of patients.
作者
张士国
ZHANG Shiguo(People's Hospital of Fuxin Mongolian Autonomous County,Fuxin 123000,China)
出处
《中国医药指南》
2021年第17期51-52,共2页
Guide of China Medicine
关键词
非糜烂性胃食管反流病
雷贝拉唑
雷尼替丁
Non-erosive gastroesophageal reflux disease
Rabeprazole
Ranitidine
