摘要
目的:探讨早期微生态肠内营养支持在食管癌术后患者快速康复中的临床应用。方法:将235例食管癌手术患者随机分为两组,对照组行传统营养支持治疗护理,研究组术后早期开始应用微生态肠内营养支持,评估两组手术后第1天、3~5天、7~10天主要营养和炎症反应指标、各管道留置时间、胃肠功能恢复情况及住院天数。结果:研究组术后各时段白蛋白水平以及术后第3~5天总蛋白水平均高于对照组(P<0.05);两组术后各时段WBC水平差异无统计学意义(P>0.05),但对CRP的恢复有影响,术后第3~5天、7~10天CRP水平差异有统计学意义(P<0.05);研究组术后胃管、胸管、腹腔引流管的拔管时间和住院时间均短于对照组(P<0.05)。结论:早期微生态肠内营养支持能保障食管癌术后患者营养代谢的平衡,达到快速康复和感染控制,值得临床应用推广。
Objective:To investigate the clinical application of early micro-ecological enteral nutrition support to the enhanced recovery of patients following surgical resection of esophageal cancer.Methods:235 patients undergoing surgical resection of esophageal cancer were randomly divided into two groups.Patients in the control group received conventional nutritional support and nursing,and those in the observational group were given early micro-ecological enteral nutrition support besides routine care.The two groups were observed and evaluated regarding the major nutritional indexes and inflammatory response indexes at day 1,3-7 and 7-10 after surgery as well as retention time of individual catheter,recovery of gastrointestinal function and length of hospital stay.Results:Patients in the observational group had significantly higher albumin levels at each time point and total protein levels at day 3-5 after surgery than those in the control group(P<0.05).Postoperative white blood cell(WBC)count was not significantly different between the two groups(P>0.05),yet early micro-ecological enteral nutrition support resulted in effect on C-reactive protein(CRP)level,with statistical difference at day 3-5 and 7-10 after surgery(P<0.05).Extubation of gastric tube,chest tube and abdominal drainage tube was earlier,and hospital stay was shorter in observational group than in control group(P<0.05).Conclusion:Early micro-ecological enteral nutrition support can ensure balanced nutritional metabolism,improve accelerated recovery and control infection in patients of esophageal cancer following surgery,and is worthy of clinical recommendation.
作者
王玉宇
蒋春霞
李丽
曹晓东
WANG Yuyu;JIANG Chunxia;LI Li;CAO Xiaodong(Department of Thoracic Surgery,Wuxi People′s Hospital Affiliated to Nanjing Medical University,Wuxi 214000,China)
出处
《皖南医学院学报》
CAS
2021年第4期395-397,401,共4页
Journal of Wannan Medical College
基金
无锡市“双百”中青年医疗卫生拔尖人才培养项目(HB2020019)
无锡市卫生健康委科技成果与适宜技术推广项目(T202009)。
关键词
食管癌
胸腔镜
早期肠内营养
肠道微生态
益生菌
快速康复
esophageal cancer
thoracoscope
early enteral nutrition
intestinal micro-ecology
probiotics
enhanced recovery
作者简介
王玉宇(1977-),女,副主任护师,(电话)13151009368,(电子信箱)qianhaiyaqianfen@163.com;通信作者:曹晓东,女,副主任护师,(电子信箱)opnm5m@163.com。
