摘要
目的探讨在宫颈癌三维图像引导近距离治疗(Image-Guided Brachytherapy,IGBT)中使用自制施源器固定器的安全性和可行性,评价自制施源器固定器的临床应用价值。方法回顾性分析2017年1月至12月于西南医科大学附属医院肿瘤科接受IGBT治疗的宫颈癌患者40例,分为试验组20例(自制施源器固定器固定)和对照组20例(胶带常规固定)。通过宫腔管顶点及基点的位置的移位率及移位度来评价施源器的位置改变,并在治疗后随访各组患者近期疗效及不良反应。结果试验组宫腔管施源器顶点和基点在左右、上下方向移位度均显著小于对照组(P<0.05),试验组施源器位移率明显小于对照组(11%vs.16.8%,χ^(2)=8.490,P=0.004),两组患者近期疗效以及急性期毒副反应相近(P>0.05)。结论使用自制施源器固定器可以在宫颈癌IGBT治疗中有效地稳定施源器,有助于精准近距离放疗,具有一定临床应用意义。
Objective To investigate the safety and feasibility of using a homemade applicator fixator in image guided brachytherapy(IGBT)for cervical cancer,and to evaluate the clinical value of the homemade applicator fixator.Methods Forty patients with cervical cancer treated with IGBT at the department of oncology in Affiliated Hospital of Southwest Medical University from January to December 2017 were retrospectively analyzed and divided into the test group(self-made applicator fixator)and the control group(adhesive tape).Positional changes of the applicator were evaluated by the rate and degree of displacement of the position of the apex and base of the uterine canal;and the short-term efficacy and acute side effects of each group were followed up after treatment.Results The displacement of the apex and base of the uterine canal applicator in the left-right and up-down directions was significantly smaller in the test group than in the control group(P<0.05).The displacement rate of the application group was significantly lower than that of the control group(11%vs.16.8%,χ2=8.490,P=0.004).The short-term efficacy and acute side effects in two groups were similar(P>0.05).Conclusion The adoption of a homemade applicator fixator can effectively stabilize the applicator in IGBT treatment of cervical cancer and contribute to precise brachytherapy,which has some clinical application significance.
作者
陈仁金
杨蕾
谭龙婧
杨波
石翔翔
CHEN Renjin;YANG Lei;TAN Longjing;YANG Bo;SHI Xiangxiang(Department of Oncology,Affiliated Hospital of Southwest Medical University,Luzhou Sichuan 646000,China)
出处
《中国医疗设备》
2021年第7期64-67,共4页
China Medical Devices
作者简介
通信作者:石翔翔,副主任技师,主要研究方向为肿瘤放射治疗技术。邮箱:uiokjh@163.com。
