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利多卡因局部麻醉联合咪达唑仑镇静在气管镜检查患者中的应用效果 被引量:1

Application effect of local anesthesia with Lidocaine combined with Midazolam sedation in patients undergoing tracheoscopic examination
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摘要 目的探讨利多卡因局部麻醉联合咪达唑仑镇静在气管镜检查患者中的应用效果。方法选取2017年1月~2018年12月于赣州市第五人民医院行支气管镜诊疗的60例患者作为研究对象,按随机投掷法将其分为参照组与研究组,每组各30例。参照组患者实施利多卡因局部麻醉,研究组患者在对照组的基础上联合咪达唑仑、芬太尼镇静。比较两组患者的检查相关情况、各时刻生理指标、不良事件总发生率及患者满意度。结果两组患者的完全清醒时间比较,差异无统计学意义(P>0.05)。研究组患者的操作时间短于参照组,视觉模拟量表(VAS)评分低于参照组,差异有统计学意义(P<0.05)。参照组患者T_(1)、T_(2)、T_(3)时刻的平均动脉压(MAP)、心率(HR)、呼吸频率(RR)均高于T_(0)时,血氧饱和度(SpO_(2))水平均低于T_(0)时,差异有统计学意义(P<0.05);研究组患者T_(1)、T_(2)、T_(3)时刻的MAP、HR均高于T_(0)时,SpO_(2)水平均低于T_(0)时,T_(1)、T_(3)时刻的RR高于T_(0)时,差异有统计学意义(P<0.05);研究组患者T_(1)、T_(2)、T_(3)时刻的MAP、HR、RR均低于参照组,SpO_(2)水平均高于参照组,差异有统计学意义(P<0.05)。研究组患者的不良事件总发生率(6.67%)低于参照组(26.67%),差异有统计学意义(P<0.05)。研究组患者的总满意度(96.67%)高于参照组(80.00%),差异有统计学意义(P<0.05)。结论局部麻醉联合咪达唑仑镇静用于气管镜检查患者中的效果显著,可维持患者体征稳定并降低相关不良事件风险,安全性高。 Objective To investigate the application effect of local anesthesia with Lidocaine combined with Midazolam sedation in patients undergoing tracheoscopic examination.Methods A total of 60 patients undergoing bronchoscopy in the Fifth People′s Hospital of Ganzhou City from January 2017 to December 2018 were selected as study subjects,and were divided into the reference group and the study group according to the random throwing method,with 30 cases in each group.The reference group was administered with Lidocaine local anesthesia,and the study group was sedated with Midazolam and Fentanyl on the basis of the reference group.The examination related conditions,physiological indexes at each moment,the total incidence of adverse events and patient satisfaction were compared between the two groups.Results There was no significant difference in the time of full wakefulness between the two groups(P>0.05).The operation time of the study group was shorter than that of the reference group,and the visual analogue scale(VAS)score was lower than that of the reference group,and the differences were statistically significant(P<0.05).The mean arterial pressure(MAP),heart rate(HR)and respiratory rate(RR)at T_(1),T_(2) and T_(3) in control group were higher than T_(0),and the blood oxygen saturation(SpO_(2))level was lower than T_(0),and the differences were statistically significant(P<0.05).In the study group,MAP and HR at moments T_(1),T_(2) and T_(3) were higher than those at moment T_(0),SpO_(2) level was lower than that at moment T_(0),and RR at moments T_(1) and T_(3) were higher than those at moment T_(0),and the differences were statistically significant(P<0.05).The MAP,HR and RR at T_(1),T_(2) and T_(3) in the study group were lower than those in the control group,and the SpO_(2) level was higher than that in the control group,and the differences were statistically significant(P<0.05).The incidence of adverse events in the study group(6.67%)was lower than that in the control group(26.67%),and the difference was statistically significant(P<0.05).The total satisfaction of the study group(96.67%)was higher than that of the control group(80.00%),and the difference was statistically significant(P<0.05).Conclusion Local anesthesia combined with Midazole sedation has a significant effect on patients undergoing tracheal examination.It can maintain the stability of patients′signs and reduce the risk of related adverse events,with high safety.
作者 许军连 邱素萍 XU Jun-lian;QIU Su-ping(Endoscopy Center,the Fifth People′s Hospital of Ganzhou City,Jiangxi Province,Ganzhou 341000,China)
出处 《中国当代医药》 CAS 2021年第17期140-143,共4页 China Modern Medicine
基金 江西省赣州市指导性科技计划项目(GZ2017ZSF280)。
关键词 局部麻醉 咪达唑仑 镇静 气管镜检查 不良事件 Local anesthesia Midazolam Sedation Bronchoscopy Adverse events
作者简介 许军连(1982-),女,主管护师,研究方向:内镜护理及护理管理。
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