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儿童腹部神经母细胞瘤的手术技巧探讨

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摘要 目的探讨儿童腹部神经母细胞瘤手术切除技巧及其对预后的影响。方法回顾性分析郑州大学第一附属医院2010年1月至2020年1月期间手术治疗腹部神经母细胞瘤患儿230例的临床资料,男144例,女86例,年龄(21±17.5)月,其中包绕腹部大血管95例。结果230例患儿中,223例手术完整或分块完全切除肿瘤(97.0%),7例(3.0%)行姑息切除,无围术期死亡病例。术中血管破裂修补6例,术后无出血及血栓形成等,腹主动脉修补后发生双侧肾功能衰竭1例,术后肾萎缩1例,乳糜腹2例,术后腹泻3例。随访时间为3 a,196例患儿获得随访,随访率为85.2%。完全切除者随访189例,存活122例;姑息切除者随访7例,存活1例。结论血管外膜下分离分块切除肿瘤对包绕腹部大血管神经母细胞瘤是可行的,可明显提高神经母细胞瘤的切除率,提高肿瘤患儿的生存率。
出处 《肿瘤基础与临床》 2021年第2期158-160,共3页 journal of basic and clinical oncology
作者简介 徐梦瑶(1995-),女,硕士在读,主要从事小儿肿瘤的相关研究,E-mail:965975934@qq.com;通信作者:杨合英(1964-),女,主任医师,硕士生导师,主要从事儿童肿瘤和小儿消化道畸形方面的研究,E-mail:fccyanghy2@zzu.edu.cn。
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