探讨脓毒性休克患者早期充分液体复苏后血乳酸清除率、中心静脉血氧饱和度(SCVO_(2))的改变,以及与疾病预后的关系被引量：3

Discuss the Changes of Serum Lactate Clearance,Central Venous Oxygen Saturation(SCVO_(2))and Prognosis of Septic Shock Patients after Early Full Fluid Resuscitation

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摘要目的分析脓毒性休克患者早期充分液体复苏后血乳酸清除率、中心静脉血氧饱和度(SCVO_(2))的改变,以及与疾病预后的关系。方法选取本院2017年1月至2020年5月诊治的60例脓毒性休克患者开展本次试验研究,所有患者均给予早期充分液体复苏治疗,将其中在3天之内存活且各项脏器功能趋向于稳定的42例患者划分为观察组,将3天之内死亡或者是病情持续恶化的18例患者划分为对照组,对比两组乳酸清除率和中心静脉血氧饱和度改变情况。结果对照组0-72h之内的乳酸水平(LAC)无明显变化(P>0.05),0-72h之内观察组的LAC水平、SCVO_(2)指标和对照组的SCVO_(2)指标均呈现出明显变化(P<0.05);与对照组的LAC水平相比,观察组明显偏低(P<0.05);与对照组的SCVO_(2)指标相比,观察组明显偏高(P<0.05)。对照组血乳酸清除率为-4.78%,观察组乳酸清除率为33.71%,与对照组血乳酸清除率相比,观察组明显偏高(P<0.05)。结论在对脓毒性休克患者展开早期充分液体复苏治疗以后,动态监测患者的血乳酸指标和中心静脉血氧饱和度能够对患者的预后效果进行有效判断,能够反应出患者的实际病情变化情况,有助于及时调整对患者的干预措施,具有推广价值。 Objective Analysis of the serum lactate clearance rate,central venous oxygen saturation(SCVO_(2))changes after early full fluid resuscitation in septic shock patients and the relationship with disease prognosis.Methods In this study,we selected 60 patients with septic shock from January 2017 to May 2020.All patients were treated with early full fluid resuscitation.42 patients who survived within 3 days and had stable organ function were divided into observation groups.18 patients who died within 3 days or whose condition continued to deteriorate were divided into control groups.Results There was no significant change in lactic acid level(LAC)within h 0-72 in the control group(P>0.05).The LAC level,SCVO_(2) index and SCVO_(2) index in the observation group and the control group showed significant changes within 0-72(P<0.05).The observation group was significantly lower than the control group(P<0.05),and the observation group was significantly higher than the control group(P<0.05).The clearance rate of lactic acid in the control group was-4.78%and 33.71%in the observation group.high(P<0.05).Conclusion After early full fluid resuscitation in septic shock patients,dynamic monitoring of blood lactic acid index and central venous oxygen saturation can effectively judge the prognosis of patients,can reflect the actual changes of the patient’s condition,help to adjust the intervention measures to patients in time,and have popularization value.

作者袁媛 YUAN Yuan(Heyuan People’s Hospital,Heyuan,Guangdong 517000)

机构地区河源市人民医院

出处《智慧健康》 2021年第2期99-100,103,共3页 Smart Healthcare

关键词脓毒性休克早期充分液体复苏血乳酸清除率中心静脉血氧饱和度疾病预后应用效果 Septic shock Early full fluid resuscitation Serum lactate clearance rate Central venous oxygen saturation Disease prognosis Application effect

分类号 R459.7 [医药卫生—急诊医学]