摘要
目的分析间输尿管镜手术不同时机行间苯三酚治疗对输尿管结石的影响。方法 120例输尿管结石患者进行研究,通过随机数表法将患者分为观察组与对照组,各60例。观察组患者于术前15 min行间苯三酚治疗,对照组患者于术后15 min行间苯三酚治疗。对比两组临床疗效、手术指标、肾绞痛疼痛情况及并发症发生情况。结果观察组治疗总有效率为98.33%高于对照组的88.33%,差异具有统计学意义(P<0.05)。观察组碎石成功率为95.00%与对照组的91.67%对比,差异无统计学意义(P>0.05)。观察组结石清除率为88.33%显著高于对照组的68.33%,复发率为1.67%显著低于对照组的21.67%,差异具有统计学意义(P<0.05)。观察组患者术后1 d、术后2个月肾绞痛疼痛评分分别为(4.32±2.13)、(3.05±1.17)分显著低于对照组的(6.27±2.08)、(4.25±1.03)分,差异具有统计学意义(P<0.05);术后6个月两组肾绞痛疼痛对比,差异无统计学意义(P>0.05)。观察组并发症发生率为1.67%显著低于对照组的13.33%,差异具有统计学意义(P<0.05)。结论在患者术前15 min采用间苯三酚对患者进行滴注治疗可有效促进患侧输尿管平滑肌的松弛扩张,减少输尿管镜进入输尿管的难度,术中有效防止患侧输尿管平滑肌痉挛,术后有效促进结石排出,值得广泛推广使用。
Objective To analyze the effect of phloroglucinol treatment at different timings of ureteroscopic surgery on ureteral calculi. Methods A total of 120 patients with ureteral calculi as study subjects were divided into observation group and control group according to random numerical table, with 60 cases in each group. Patients in the observation group were treated with phloroglucinol 15 min before surgery, and patients in the control group were treated with phloroglucinol 15 min after surgery. The clinical efficacy, surgical indicators, renal colic pain and occurrence of complications were compared between the two groups. Results The total effective rate of the observation group was 98.33%, which was higher than 88.33% of the control group, and the difference was statistically significant(P<0.05). The success rate of lithotripsy of the observation group was 95.00%, which had no statistically significant difference compared with 91.67% of the control group(P>0.05). The stone clearance rate 88.33% of the observation group was significantly higher than 68.33% of the control group, and recurrence rate 1.67% was significantly lower than 21.67% of the control group. All the difference was statistically significant(P<0.05). The renal colic pain score at 1 d and 2 months after surgery of the observation group were(4.32±2.13) and(3.05±1.17) points, which were significantly lower than(6.27±2.08) and(4.25±1.03) points of the control group, and the difference was statistically significant(P<0.05). There was no statistically significant difference in renal colic pain at 6 months after surgery between the two groups(P>0.05). The incidence of complications 1.67% of the observation group was significantly lower than 13.33% of the control group, and the difference was statistically significant(P<0.05). Conclusion Phloroglucinol infusion 15 min before surgery can effectively promote the relaxation and expansion of the affected ureteral smooth muscle, reduce the difficulty of ureteroscopy entering, effectively prevent the spasm of the affected ureteral smooth muscle during surgery, and effectively promote the discharge of stones after surgery, which is worthy of wide promotion and application.
作者
周盛涛
周明伟
ZHOU Sheng-tao;ZHOU Ming-wei(Department of Urology,Dongguan Renkang Hospital,Dongguan 523952,China)
出处
《中国实用医药》
2021年第10期147-149,共3页
China Practical Medicine
基金
2020年东莞市社会科技发展(一般)项目(项目编号:202050715065140)。
关键词
间苯三酚
钬激光碎石
气压弹碎石
输尿管结石
肾绞痛
Phloroglucinol
Holmium laser lithotripsy
Pneumatic lithotripsy
Ureteral calculi
Renal colic
