摘要
目的:系统评价艾灸疗法对慢性疲劳综合征的临床效果,以期为临床应用提供循证依据。方法:计算机检索PubMed、EMBase、The Cochrane Library、Web of Science、CNKI、CINAHL、CBM、VIP、WANFANG Data数据库中有关艾灸疗法治疗慢性疲劳综合征的随机对照试验,检索时间均为建库至2020年5月7日,使用风险评估工具评估文献质量,RevMan 5.3软件进行Meta分析。结果:最终纳入13篇,共911例患者,Meta分析结果显示,艾灸疗法干预慢性疲劳综合征总有效率升高[OR=5.34,95%CI(3.58,7.97),P<0.00001],FS-14[MD=-2.65,95%CI(-4.25,-1.05),P=0.00001]、中医症状积分[MD=-7.20,95%CI(-10.12,-4.27),P<0.00001]降低,与对照组比较,差异均具有统计学意义。结论:艾灸疗法干预慢性疲劳综合征能够有效改善患者的临床症状,且安全性较高。纳入的文献质量偏低,使论证强度受一定限制,需要更多的高质量、大样本多中心的RCT评价其临床效果。
Objective:To systematically evaluate the effect of moxibustion therapy on chronic fatigue syndrome(CFS)in order to provide evidence-based evidence for clinical application.Methods:Randomized controlled trials of moxibustion therapy for CFS in PubMed,Embase,The Cochrane Library,Web of Science,CNKI,CINAHL,CBM,VIP and WanFang Data were searched by computer.The retrieval time was from database establishment to April 7,2020.Risk assessment tools were used to evaluate literature quality and RevMan 5.3 software was used for Meta analysis.Results:A total of 13 articles were included,including a total of 911 patients.Meta analysis results showed that the total effective rate of moxibustion therapy in the treatment of chronic fatigue syndrome was increased[OR=5.34,95%CI(3.58,7.97),P<0.00001],fatigue scale-14[MD=-2.65,95%CI(-4.25,-1.05),P=0.00001]and TCM syndrome score[MD=-7.20,95%CI(-10.12,-4.27),P<0.00001]was discreased.All of them had statistical significance compared with control group.Conclusion:Moxibustion therapy could effectively improve the clinical symptoms of patients with chronic fatigue syndrome with high safety.However,the quality of the included literatures is low,so the intensity of demonstration is limited to a certain extent.More high-quality,large sample and multi-center RCT is still needed to evaluate the efficacy of moxibustion therapy.
作者
王苗苗
马淑丽
杨莉霞
孔祥菡
郭玉
王姝
Wang Miaomiao;Ma Shuli;Yang Lixia;Kong Xianghan;Guo Yu;Wang Shu(Shanxi University of Chinese Medicine,Jinzhong Shanxi 030619;Shanxi Provincial People`s Hospital,Taiyuan Shanxi 030012)
出处
《山西中医药大学学报》
2021年第1期19-23,共5页
Journal of Shanxi University of Chinese Medicine
基金
山西省软科学研究计划项目(2016041033-4)。
关键词
艾灸
慢性疲劳综合征
META分析
moxibustion therapy
chronic fatigue syndrome
Meta-aanalysis
作者简介
王苗苗,硕士研究生,Email:dw10121117@163.com;通讯作者:马淑丽,副教授,硕士研究生导师,Email:shuli.ma@163.com。
