摘要
目的探讨不同术式对儿童腺样体肥大的治疗疗效。方法回顾性分析该院和山西省煤炭中心医院2016年10月-2018年11月接受治疗的儿童腺样体肥大患儿91例临床资料,将采用鼻内镜下等离子消融术患儿46例纳入观察组,将采用鼻内镜下腺体刮除术患儿45例纳入对照组。对比两组患儿临床疗效、术中指标及手术前后血管内皮生长因子(VEGF)、白介素-17(IL-17)及白介素-8(IL-8)水平变化。结果观察组有效率为91.30%,高于对照组75.56%,差异有统计学意义(χ^(2)=4.098,P<0.05),观察组术中出血量(6.13±3.12)mL、症状缓解时间(7.53±3.11)d及手术时间(8.62±4.67)min均较对照组低,且术后VEGF(40.12±7.21)pg/mL、IL-17(26.12±3.43)pg/mL、IL-8(176.37±26.24)pg/mL水平较对照组低,差异有统计学意义(P<0.05)。结论腺样体肥大儿童采取鼻内镜下等离子消融术的疗效较为显著,能够有效缩短手术时间、减少出血量,降低IL-17、IL-8、VEGF等因子分泌,促进康复。
Objective To explore the therapeutic effects of different surgical procedures on children with adenoid hypertrophy. Methods The clinical data of 91 children with adenoid hypertrophy who were treated in the hospital and Shanxi Coal Central Hospital from October 2016 to November 2018 were retrospectively analyzed, and 46 children with plasma ablation under nasal endoscopy were included in the observation group, 45 children who underwent nasal endoscopic gland curettage were included in the control group. The clinical efficacy, intraoperative indexes, and changes of vascular endothelial growth factor(VEGF), interleukin-17(IL-17) and interleukin-8(IL-8) levels before and after the operation were compared between the two groups. Results The effective rate of observation group was 91.30%, which was higher than that of control group 75.56%, the difference was statistically significant(χ^(2)=4.098, P <0.05). In the observation group,intraoperative blood loss was(6.13±3.12)mL, symptom relief time(7.53±3.11)d and operation time(8.62±4.67)min were lower than those of the control group, and the levels of VEGF(40.12±7.21)pg/mL, IL-17(26.12±3.43)pg/mL, and IL-8(176.37±26.24)pg/mL were lower than those of the control group, the difference was statistically significant(P <0.05). Conclusion Endoscopic plasma ablation in children with adenoid hypertrophy is more effective. It can effectively shorten the operation time, reduce the amount of bleeding, reduce the secretion of IL-17, IL-8, VEGF and other factors, and promote recovery.
作者
姚海波
庞涛
王晓慧
YAO Hai-bo;PANG Tao;WANG Xiao-hui(Department of Otolaryngology,Beijing Aiyuhua Women's and Children's Hospital,Beijing,100176 China;Department of Otorhinolaryngology,Shanxi Coal Central Hospital,Taiyuan,Shanxi Province,030000 China)
出处
《中外医疗》
2021年第5期70-72,共3页
China & Foreign Medical Treatment
作者简介
姚海波(1985-),男,本科,主治医师,研究方向为咽耳鼻喉。
