摘要
目的了解安徽省钩端螺旋体病流行特征,为制定防治对策提供科学依据。方法用描述性流行病学方法对2015—2019年安徽省钩端螺旋体病流行特征进行分析,采用病原学、血清学检测方法探索主要的流行菌群。结果2015—2019年安徽省钩体病年平均发病率为0.028/10万,发病最高年份是2016年(0.077/10万),职业以农民为主,占96.47%(82/85)。年龄以15~60岁为主,占60.00%(51/85),男女之比为2.04∶1(57/28)。病例主要分布在怀远县(63例)、旌德县(8例)和黄山区(6例)。2015—2019年从1858只黑线姬鼠中分离培养出钩体菌122株,均为黄疸出血群。自然人群血清学共检测2028份,阳性134份,阳性率6.61%,以黄疸出血群为主,占88.06%(118/134)。结论近年钩体病流行血清群与20世纪70年代相比发生了较大变化,安徽省钩端螺旋体病流行菌群为黄疸出血群,主要宿主是黑线姬鼠,需长期监测,及时掌握疫情动态,有针对性地进行预防控制。
Objective To study the epidemiological characteristics of leptospirosis in Anhui Province,and to provide scientific basis for formulating prevention and treatment countermeasures.Methods Epidemiological characteristics of leptospirosis in Anhui Province from 2015 to 2019 were analyzed by descriptive epidemiological methods,and pathogenic and serological detection methods were used to explore the main microbial population.Results The average morbidity of leptospirosis in Anhui Province from 2015 to 2019 was 0.028/100000,and the highest incidence was 0.077/100000 in 2016.The major patients were farmers(96.47%,82/85).The majority was aged from 15 years to 60 years(60.00%),and the ratio of male to female was 2.04∶1.Most cases were found in Huaiyuan County(63 cases),followed by Jinde County(8 cases)and Huangshan District(6 cases).From 2015 to 2019,122 strains of Leptospirosis were isolated and cultured from 1858 leptospirosis rats,all of which were jaundice hemorrhagic groups.The positive rate of serology was 6.61%(134/2028),and the jaundice bleeding group accounted for 88.06%(118/134).Conclusion In recent years,the serogroup of leptospirosis epidemic has changed greatly from the 1970s in Anhui Province,the main epidemic microbial population leptospirosis is jaundice bleeding group,and the dominant host is Apodemus agnarius.It is necessary to monitor epidemic for a long time and keep abreast of the epidemic situation and carry out targeted prevention and control.
作者
李青
张竹慧
LI Qing;ZHANG Zhu-hui(Anhui Provincial Center for Disease Control and Prevention,Hefei 230061,China)
出处
《中华卫生杀虫药械》
CAS
2021年第1期71-73,共3页
Chinese Journal of Hygienic Insecticides and Equipments
基金
全国重点传染病及病媒生物监测项目(编号:2014-36-W-496)。
关键词
钩端螺旋体病
流行病学研究
哨点监测
leptospirosis
epidemiologic studies
sentinel surveillance
作者简介
李青(1979-),男,安徽亳州市人,副主任医师,主要从事应急管理与疾病预防控制工作。