摘要
目的分析甘肃省定西市安定区2008—2018年手足口病的流行病学及病原体特征,为手足口病的防控提供科学有效的依据。方法收集2008—2018年定西市安定区手足口病疫情资料和实验室诊断结果,采用描述性流行病学方法进行分析。结果甘肃省定西市安定区2008—2018年报告手足口病确诊病例2 830例,年平均发病率为59.22/10万;夏秋季是流行季节,6月份为发病高峰,发病数占总病例数的27.63%(782/2 830),10月份为发病次高峰,占11.20%(317/2 830);男女发病比例为1.55∶1;确诊病例年龄主要集中在1~5岁,占发病数的76.89%(2 176/2 830),其中3~4岁儿童所占比例最高,占22.58%(639/2 830);发病以散居儿童为主,占52.69%(1 491/2 830),其次为幼托儿童和学生,分别占31.20%(883/2 830)和15.62%(442/2 830);安定区21个乡镇/街道办均有报告病例,中华路街道办事处、永定路街道办事处、内官营镇、符川镇、凤翔镇发病数位居前5位,占发病总数的73.64%(2 084/2 830)。手足口病实验室诊断330例,其中肠道病毒71型、柯萨奇病毒A组16型和其他肠道病毒分别占33.64%(111/330)、37.58%(124/330)和28.79%(95/330)。结论甘肃省定西市安定区5—6月手足口病开始多发,1~5岁幼儿为主要感染对象,应在幼儿学龄前每年2月份加强疫苗的免疫接种,从而有效地预防手足口病的暴发及重症感染。
Objective To analyze the epidemiology and pathogenic characteristics on hand foot and mouth disease(HFMD) in Anding district of Dingxi city from 2008 to 2018. Methods HFMD epidemic data and laboratory test results from 2008 to 2018 were collected for epidemiological analysis. Results From 2008 to 2018, a total of 2 830 HFMD cases were reported in Anding district of Dingxi city with an average annual incidence of 59.22/100 000.The epidemic season was summer and autumn, with the peak in June(27.63%, 782/2 830) and the second peak in October(11.20%, 317/2 830).The incidence ratio of male to female was 1.55∶1.Cases were concentrated in children aged 1-5 years, accounting for 76.89%(2 176/2 830) of the reported cases.Among them, the incidence rate was the highest in the age of 3-4(22.58%, 639/2 830).The majority of the cases were scattered children, accounting for 52.69%(1 491/2 830), followed by children in preschool care(31.20%, 883/2 830) and students(15.62%, 442/2 830).Cases were reported in 21 towns(or street offices) in Anding district, and the cases in Zhonghua Road Street office, Yongding Road street office, Neiguan Town, Fuchuan Town and Fengxiang Town ranked top 5, accounting for 73.64%(2 084/2 830) of the total number of cases;330 HFMD cases were detected, 33.64%(111/330) were found to be positive for human enterovirus 71(EV-A71), 37.58%(124/330) were found to be positive for coxasckievirus A16(CV-A16)and the others was 28.79%(95/330). Conclusions HFMD occurrs frequently from May to June in Anding District of Dingxi City,and children aged 1-5 years old are the main infection objects.
作者
马丽娜
刘思强
MA Li-na;LIU Si-qiang(Gansu University of Chinese Medicine in Dingxi Campus,Dingxi,Gansu 743000,China)
出处
《中国病毒病杂志》
CAS
2021年第1期33-37,共5页
Chinese Journal of Viral Diseases
基金
甘肃省高等学校创新能力提升项目(2019B-230)
甘肃省高等学校创新基金项目(2020A-193)
甘肃中医药大学定西校区科研项目(2019XJYB03)。
关键词
手足口病
流行病学
发病率
Hand
foot and mouth disease
Epidemiology
Morbidity
作者简介
马丽娜,硕士,主要研究方向为医学微生物和流行病学调查;通信作者:马丽娜,E-mail:472929903@qq.com。
